LOX and DPT

Number of citations of the paper that reports this interaction (PubMedID 8082810)
0

Data Source:
HPRD (in vivo)

		LOX	DPT
Description		lysyl oxidase	dermatopontin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Extracellular Matrix	Extracellular Region Extracellular Space Extracellular Matrix
	Molecular Function	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor Small Molecule Binding Metal Ion Binding Molecular Adaptor Activity	Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Blood Vessel Development Osteoblast Differentiation Heart Development Response To Xenobiotic Stimulus Response To Hormone Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Aorta Development Ascending Aorta Development Descending Aorta Development Protein Modification Process Regulation Of Apoptotic Process Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Muscle Cell Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway	Cell Adhesion Negative Regulation Of Cell Population Proliferation Collagen Fibril Organization
Pathways		Elastic fibre formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Keratoconus ( 33649486) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Waist circumference adjusted for body mass index ( 34021172) Youthful appearance (self-reported) ( 32339537)	Blood protein levels ( 30072576) Diisocyanate-induced asthma ( 25918132) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Morbidity-free survival ( 17903295) PR interval ( 32439900) Rosacea symptom severity ( 29771307)
Interacting Genes		8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 MRE11	4 interacting genes: BAG6 DCN LOX TGFB1
Entrez ID		4015	1805
HPRD ID		01087	00510
Ensembl ID		ENSG00000113083	ENSG00000143196
Uniprot IDs		B0AZT2 B7ZAJ4 D0PNI2 P28300	Q07507
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Chromatin Nucleosome Nucleosome Assembly Nucleosome Organization Chromatin Remodeling Chromosome Protein-DNA Complex Assembly Chromatin Organization Innate Immune Response In Mucosa Double-stranded DNA Binding Negative Regulation Of DNA Metabolic Process Regulation Of DNA Recombination Phosphatidylinositol Phosphate Binding Mucosal Immune Response Organ Or Tissue Specific Immune Response Chromosome Condensation Nucleosomal DNA Binding Regulation Of DNA Metabolic Process Negative Regulation Of DNA Recombination Mitochondrial Double-strand Break Repair Via Homologous Recombination Nicotinamide Phosphoribosyltransferase Activity Polyprenol Biosynthetic Process Dehydrodolichyl Diphosphate Synthase Complex Ditrans,polycis-polyprenyl Diphosphate Synthase [(2E,6E)-farnesyl Diphosphate Specific] Activity Euchromatin Antibacterial Humoral Response Myosin II Heavy Chain Binding Histone H2AXY142 Phosphatase Activity Chromatin DNA Binding	Glycosaminoglycan Catabolic Process Hyaluronan Catabolic Process Hyaluronan Metabolic Process Muscle Cell Cellular Homeostasis Extracellular Matrix Assembly T Cell Activation Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Striated Muscle Tissue Development Regulation Of Muscle Organ Development Glycosaminoglycan Metabolic Process Extracellular Region Collagen Binding Microvillus Regulation Of Developmental Process Extracellular Matrix Negative Regulation Of Endothelial Cell Migration Descending Aorta Development Ascending Aorta Development Connective Tissue Development Branch Elongation Involved In Mammary Gland Duct Branching Positive Regulation Of Microglia Differentiation Cellular Response To Acetaldehyde Lymphocyte Activation Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Leukocyte Activation Positive Regulation Of Monocyte Aggregation Anatomical Structure Morphogenesis Macrophage Migration Inhibitory Factor Receptor Complex Animal Organ Development Golgi Lumen Regulation Of Multicellular Organismal Development Lung Development Positive Regulation Of Primary MiRNA Processing Embryonic Liver Development Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Cell Activation Monocyte Aggregation Peptidyl-lysine Oxidation Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Frontal Suture Morphogenesis BAT3 Complex Negative Regulation Of Hyaluronan Biosynthetic Process Positive Regulation Of Exit From Mitosis Negative Regulation Of Skeletal Muscle Tissue Development Type III Transforming Growth Factor Beta Receptor Binding Langerhans Cell Differentiation Maintenance Of Unfolded Protein Carbohydrate Derivative Catabolic Process Positive Regulation Of ERK1 And ERK2 Cascade
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