LOX and DHDDS

Number of citations of the paper that reports this interaction (PMID 15110773)
4

Data Source:
HPRD (two hybrid)

		LOX	DHDDS
Gene Name		lysyl oxidase	dehydrodolichyl diphosphate synthase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Trimer Extracellular Space Nucleus	Endoplasmic Reticulum Membrane
	Molecular Function	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding	Protein Binding Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups
	Biological Process	Blood Vessel Development Cellular Protein Modification Process Extracellular Matrix Organization Collagen Fibril Organization Lung Development Wound Healing Response To Drug Elastic Fiber Assembly Response To Steroid Hormone Oxidation-reduction Process	Dolichol-linked Oligosaccharide Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Collagen formation Crosslinking of collagen fibrils Elastic fibre formation Assembly of collagen fibrils and other multimeric structures	Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Synthesis of Dolichyl-phosphate Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Post-translational protein modification Defective ALG3 causes ALG3-CDG (CDG-1d) Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Synthesis of substrates in N-glycan biosythesis Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS		Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-Protein Interactions		7 interactors: DHDDS DPT ELN HIST1H1A HIST1H1B HIST1H2BJ HIST2H2BE	3 interactors: LOX ND1 NPC2
Entrez ID		4015	79947
HPRD ID		01087	12183
Ensembl ID		ENSG00000113083	ENSG00000117682
Uniprot IDs		B7ZAJ4 D0PNI2 P28300	Q86SQ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging DNA Conformation Change Innate Immune Response In Mucosa Cellular Macromolecular Complex Assembly Antibacterial Humoral Response Chromatin Organization Antimicrobial Humoral Response Mucosal Immune Response Cellular Component Assembly Chromosome Organization Protein Complex Assembly Defense Response To Gram-positive Bacterium Organelle Organization Defense Response To Bacterium Dolichyl Diphosphate Biosynthetic Process Establishment Of Protein Localization To Chromatin Humoral Immune Response Protein Localization To Chromatin Positive Regulation Of Histone H3-K9 Methylation Stress Fiber Assembly Extracellular Matrix Organization Extracellular Structure Organization Response To Bacterium Protein Localization To Chromosome Positive Regulation Of Histone Methylation	Regulation Of Isoprenoid Metabolic Process Elastic Fiber Assembly Intracellular Cholesterol Transport Intracellular Sterol Transport Glycolipid Transport Extracellular Matrix Assembly
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	agglutinin appearance cone degeneration dehydrodolichol diphosphate enzymatic injected insufficient knocked missing mo modeling morpholino oligonucleotides outer peanut photoreceptor pigmentosa pna recessive respond retinal retinas retinitis rp segments visual zebrafish
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	agglutinin appearance cone degeneration dehydrodolichol diphosphate enzymatic injected insufficient knocked missing mo modeling morpholino oligonucleotides outer peanut photoreceptor pigmentosa pna recessive respond retinal retinas retinitis rp segments visual zebrafish
Tagcloud (Intersection) ?