LRP12 and SNAPIN

Number of citations of the paper that reports this interaction (PubMedID 12809483)
0

Data Source:
HPRD (two hybrid)

		LRP12	SNAPIN
Description		LDL receptor related protein 12	SNAP associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Clathrin-coated Pit Membrane	Golgi Membrane Acrosomal Vesicle Manchette Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Cytosol Synaptic Vesicle Membrane Secretory Granule Synaptic Vesicle Membrane BLOC-1 Complex Cytoplasmic Vesicle Synapse Perinuclear Region Of Cytoplasm Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm Microvesicle
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Integrin Binding Protein Binding	SNARE Binding Protein Binding
	Biological Process	Neuron Migration Endocytosis Cell Adhesion Signal Transduction Cell Migration Neuron Projection Development Integrin Activation Regulation Of Growth Lymphocyte Migration Into Lymphoid Organs	Intracellular Protein Transport Exocytosis Lysosome Organization Lysosomal Lumen Acidification Chemical Synaptic Transmission Neurotransmitter Secretion Anterograde Axonal Transport Retrograde Axonal Transport Endosome To Lysosome Transport Negative Regulation Of Neuron Projection Development Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Neuron Projection Development Protein-containing Complex Localization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Melanosome Organization Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Protein Maturation Establishment Of Vesicle Localization Regulation Of Lysosome Size Neuron Cellular Homeostasis Organelle Transport Along Microtubule Terminal Button Organization Autophagosome Maturation Late Endosome To Lysosome Transport Positive Regulation Of Late Endosome To Lysosome Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways		Retinoid metabolism and transport	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Daytime nap ( 33568662) Glaucoma (primary open-angle) ( 22570617) HOMA-B (corrected for HOMA-IR) ( 30369944) Impulsivity (attentional) ( 30718321) Irritable mood ( 29500382) Periodontitis (DPAL) ( 24024966) Systolic blood pressure ( 28739976) Vascular endothelial growth factor levels ( 21757650)
Interacting Genes		7 interacting genes: ACTN2 MYOT NMRK2 RACK1 SNAPIN SNCA ZFYVE9	103 interacting genes: ABI2 ACTN2 ATG14 ATP1A1 BANP BFSP1 BFSP2 BIN1 BLOC1S1 BLOC1S2 BLOC1S4 BLOC1S5 BLOC1S6 BNIPL C20orf202 CCDC102B CDC42BPA CEP170 CMYA5 CSNK1D DDR1 DENND1C DES DNM2 DOCK9 DST DTNBP1 DYRK3 DYSF EBAG9 EEF1G ELP1 ENO3 EXOC7 FAM114A1 FSD2 GPRASP1 GRIK1 HAP1 HMGB2 IKBIP IMMT KANK2 KAT5 KAT7 KIF5C KPNB1 KRT10 KRT15 KRT16 KRT17 KRT19 KRT20 KRT24 KRT26 LAMA2 LAMC1 LMNB1 LRP12 MACF1 MAPK14 MET MORC3 MTNR1A MYH14 MYH3 MYH7 NECAB2 NEDD9 NME7 NUP62CL PCYT1A PLAC9 PLEC PRKACA RABEP1 RABGEF1 RETREG1 RGS7 RNF13 SHBG SKA1 SMAD2 SMG1 SNAP23 SNAP25 SPAG5 SPP1 SPTB SPTBN1 ST7 TFIP11 TOMM70 TPM1 TPM2 TPM3 TPM4 TRIM63 TRPV1 TSG101 WASHC3 YWHAE YWHAZ
Entrez ID		29967	23557
HPRD ID		17447	06111
Ensembl ID		ENSG00000147650	ENSG00000143553
Uniprot IDs		Q59H02 Q9Y561	O95295
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Domain Specific Binding Structural Constituent Of Muscle Positive Regulation Of Transport Actin Cytoskeleton Actin Filament Uncapping Regulation Of Vesicle-mediated Transport Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Synaptic Vesicle Transport SNARE Binding Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neuronal Cell Body Positive Regulation Of Late Endosome To Lysosome Transport Actin Binding Positive Regulation Of Protein Localization To Cell Periphery Enzyme Activator Activity Titin Z Domain Binding Cytoplasm Negative Regulation Of Transport Regulation Of Membrane Potential Neurotransmitter Transport Regulation Of Neurotransmitter Secretion Vesicle-mediated Transport In Synapse Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process IRE1-RACK1-PP2A Complex Negative Regulation Of Translational Frameshifting Nicotinate Riboside Kinase Activity Cell Junction Organization Regulated Exocytosis Establishment Of Vesicle Localization Regulation Of Cellular Localization Positive Regulation Of Cation Transmembrane Transport Phospholipase C-activating Angiotensin-activated Signaling Pathway Positive Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Vesicle Localization Ribosylnicotinate Kinase Activity Ribosylnicotinamide Kinase Activity Cell Projection Positive Regulation Of Intracellular Transport Microspike Assembly Z Disc	Cytoskeleton Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Organelle Organization Intermediate Filament Organization Establishment Of Organelle Localization Intermediate Filament Supramolecular Fiber Organization Organelle Localization Structural Constituent Of Cytoskeleton BLOC-1 Complex Actin Filament Binding Synaptic Vesicle Transport Establishment Of Vesicle Localization Structural Molecule Activity Axo-dendritic Transport Axon Cytoplasm Axonal Transport Vesicle Localization Establishment Of Localization In Cell Anterograde Axonal Transport Cytosol Anterograde Synaptic Vesicle Transport Muscle Thin Filament Tropomyosin Structural Constituent Of Skin Epidermis Cytoplasm Transport Along Microtubule Vesicle Transport Along Microtubule Cellular Localization Cytoskeleton-dependent Intracellular Transport Vesicle Cytoskeletal Trafficking Regulation Of Cellular Component Organization Microtubule-based Transport Melanosome Organization Keratin Filament Intracellular Transport Pigment Granule Organization Structural Constituent Of Muscle Actomyosin Structure Organization Muscle System Process Actin Binding Muscle Contraction Extracellular Exosome Contractile Muscle Fiber Stress Fiber Organelle Transport Along Microtubule Tissue Morphogenesis Intracellular Protein Localization Z Disc
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