LRP12 and NMRK2

Number of citations of the paper that reports this interaction (PMID 12809483)
4

Data Source:
HPRD (in vivo, two hybrid)

		LRP12	NMRK2
Gene Name		low density lipoprotein receptor-related protein 12	nicotinamide riboside kinase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Coated Pit Integral Component Of Membrane	Intracellular
	Molecular Function	Low-density Lipoprotein Receptor Activity Protein Binding	Protein Binding ATP Binding Metal Ion Binding Ribosylnicotinamide Kinase Activity
	Biological Process	Endocytosis Receptor-mediated Endocytosis Signal Transduction Regulation Of Growth	NAD Biosynthetic Process Phosphorylation Negative Regulation Of Myoblast Differentiation
Pathways		Visual phototransduction Diseases associated with visual transduction Retinoid metabolism and transport
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 22570617) Vascular endothelial growth factor levels ( 21757650)
Protein-Protein Interactions		6 interactors: ACTN2 GNB2L1 MYOT NMRK2 SNAPIN ZFYVE9	7 interactors: APP CDKN1A IGF2 ITGB1 LRP12 SAT1 ST7
Entrez ID		29967	27231
HPRD ID		17447	16371
Ensembl ID		ENSG00000147650	ENSG00000077009
Uniprot IDs		Q59H02 Q9Y561	B7ZKR3 Q9NPI5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of CAMP Catabolic Process Terminal Button Organization Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Autophagic Vacuole Maturation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Muscle Contraction Microspike Assembly Regulation Of Cellular Localization Negative Regulation Of Oxidative Stress-induced Neuron Death Muscle System Process Negative Regulation Of Protein Localization To Cell Surface SMAD Protein Import Into Nucleus Positive Regulation Of Protein Homooligomerization Positive Regulation Of Gastrulation Negative Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Mitochondrial Depolarization Synaptic Vesicle Fusion To Presynaptic Membrane Exocytosis Regulation Of Hydrogen Peroxide-induced Cell Death SMAD Protein Complex Assembly Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Phagocytosis Synaptic Vesicle Maturation Negative Regulation Of Potassium Ion Transmembrane Transport Vesicle-mediated Transport Negative Regulation Of Transport Positive Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Mitochondrial Depolarization Positive Regulation Of Protein Oligomerization Regulation Of Protein Localization To Cell Surface Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Negative Regulation Of Potassium Ion Transport Negative Regulation Of Myoblast Differentiation Secretion By Cell Negative Regulation Of Oxidative Stress-induced Cell Death Regulation Of Protein Oligomerization Regulation Of Potassium Ion Transmembrane Transporter Activity Anterograde Axon Cargo Transport NAD Biosynthetic Process Regulation Of Response To Reactive Oxygen Species Positive Regulation Of Potassium Ion Transport Viral Process Endosome To Lysosome Transport Positive Regulation Of Embryonic Development Actin-myosin Filament Sliding See more	Response To Radiation Regulation Of Growth Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Cycle Process Learning Or Memory Signaling Cell Communication Positive Regulation Of Cell Cycle Cognition Regulation Of Cell Cycle Response To Light Stimulus Cellular Response To Ionizing Radiation Visual Learning Regulation Of Protein Phosphorylation Visual Behavior Cellular Response To Stimulus Response To Abiotic Stimulus Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cellular Response To Mechanical Stimulus Regulation Of Mitotic Cell Cycle Platelet Degranulation Blood Coagulation Hemostasis Associative Learning Positive Regulation Of Protein Metabolic Process Single-organism Behavior Developmental Cell Growth Response To Extracellular Stimulus Regulation Of Phosphorylation Regulation Of Cell Cycle Process Regulation Of Cellular Ketone Metabolic Process Response To Drug Vesicle-mediated Transport Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Regulation Of Body Fluid Levels Positive Regulation Of Lymphocyte Proliferation Transport Behavior Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Regulation Of Receptor Activity Wound Healing Spermidine Acetylation Synaptic Growth At Neuromuscular Junction Response To Stimulus Learning Cellular Response To Radiation Signal Transduction See more
Tagcloud ?		as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc gas7 glaugen human660w interrogated kilobases merit myoc neighbor optn penncnv poag quad six1 six6 srbd1 tmco1 wdr36 zfpm2
Tagcloud (Difference) ?		as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc gas7 glaugen human660w interrogated kilobases merit myoc neighbor optn penncnv poag quad six1 six6 srbd1 tmco1 wdr36 zfpm2
Tagcloud (Intersection) ?