LRP12

Description		LDL receptor related protein 12
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Clathrin-coated Pit Membrane
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Integrin Binding Protein Binding
	Biological Process	Neuron Migration Endocytosis Cell Adhesion Signal Transduction Cell Migration Neuron Projection Development Integrin Activation Regulation Of Growth Lymphocyte Migration Into Lymphoid Organs
Pathways		Retinoid metabolism and transport
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Daytime nap ( 33568662) Glaucoma (primary open-angle) ( 22570617) HOMA-B (corrected for HOMA-IR) ( 30369944) Impulsivity (attentional) ( 30718321) Irritable mood ( 29500382) Periodontitis (DPAL) ( 24024966) Systolic blood pressure ( 28739976) Vascular endothelial growth factor levels ( 21757650)
Novel Interacting Genes		1 novel interacting genes: PABPC1
Interacting Genes		7 interacting genes: ACTN2 MYOT NMRK2 RACK1 SNAPIN SNCA ZFYVE9
Entrez ID		29967
HPRD ID		17447
Ensembl ID		ENSG00000147650
Uniprot IDs		Q59H02 Q9Y561
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Domain Specific Binding Structural Constituent Of Muscle Positive Regulation Of Transport Actin Cytoskeleton Actin Filament Uncapping Regulation Of Vesicle-mediated Transport Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Synaptic Vesicle Transport SNARE Binding Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neuronal Cell Body Positive Regulation Of Late Endosome To Lysosome Transport Actin Binding Positive Regulation Of Protein Localization To Cell Periphery Enzyme Activator Activity Titin Z Domain Binding Cytoplasm Negative Regulation Of Transport Regulation Of Membrane Potential Neurotransmitter Transport Regulation Of Neurotransmitter Secretion Vesicle-mediated Transport In Synapse Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process IRE1-RACK1-PP2A Complex Negative Regulation Of Translational Frameshifting Nicotinate Riboside Kinase Activity Cell Junction Organization Regulated Exocytosis Establishment Of Vesicle Localization Regulation Of Cellular Localization Positive Regulation Of Cation Transmembrane Transport Phospholipase C-activating Angiotensin-activated Signaling Pathway Positive Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Vesicle Localization Ribosylnicotinate Kinase Activity Ribosylnicotinamide Kinase Activity Cell Projection Positive Regulation Of Intracellular Transport Microspike Assembly Z Disc
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