TCHP and NDOR1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TCHP	NDOR1
Gene Name		trichoplein, keratin filament binding	NADPH dependent diflavin oxidoreductase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Plasma Membrane Keratin Filament Apical Cortex	Nucleus Cytoplasm Cytosol Intermediate Filament Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	NADPH-hemoprotein Reductase Activity Iron Ion Binding Protein Binding FMN Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Growth	Cell Death Iron-sulfur Cluster Assembly Cellular Response To Menadione Small Molecule Metabolic Process Oxidation-reduction Process
Pathways			Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Metabolite levels (MHPG) ( 23319000)
Protein-Protein Interactions		21 interactors: CCDC172 CCDC85B CDR2 DYDC1 KRT14 KRT15 KRT16 KRT18 KRT40 KRT5 KRT6A KRT8 LZTS2 MIPOL1 MKRN3 NAB2 NDOR1 NME7 TEX11 TRIM27 VIM	8 interactors: CCDC33 CIAPIN1 CYCS DLG4 EFHC2 MTUS2 TCF4 TCHP
Entrez ID		84260	27158
HPRD ID		14403	10444
Ensembl ID		ENSG00000139437	ENSG00000188566
Uniprot IDs		Q9BT92	D3YTG6 Q9UHB4
PDB IDs			4H2D
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Developmental Process Cytoskeleton Organization Anatomical Structure Development Epidermis Development Hemidesmosome Assembly Epithelium Development Organelle Organization Hepatocyte Apoptotic Process Intermediate Filament Organization Cellular Component Assembly Tumor Necrosis Factor-mediated Signaling Pathway Response To Zinc Ion Cell-substrate Junction Assembly Tissue Development Golgi To Plasma Membrane CFTR Protein Transport Cellular Response To Menadione Negative Regulation Of Interleukin-2 Secretion Organ Development Cellular Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Hair Cycle Meiotic Gene Conversion Response To Tumor Necrosis Factor Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Response To Inorganic Substance Negative Regulation Of Calcium Ion Import Male Meiosis Chromosome Segregation Intermediate Filament Bundle Assembly Cell Differentiation Response To Ionizing Radiation Cell Death Death Keratinocyte Migration Negative Regulation Of Transcription From RNA Polymerase III Promoter Epithelial Cell Differentiation Response To Hydrostatic Pressure Bergmann Glial Cell Differentiation Viral Process Interferon-gamma Secretion Chiasma Assembly	Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Apoptotic Process Programmed Cell Death Vesicle Localization Maintenance Of DNA Repeat Elements Mitochondrial Electron Transport, Cytochrome C To Oxygen Cell Death Death Negative Regulation Of Growth Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Maintenance Of Apical/basal Cell Polarity Embryonic Genitalia Morphogenesis Receptor Localization To Synapse Myoblast Fate Commitment Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Receptor Internalization Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Secretory Granule Localization Locomotory Exploration Behavior Regulation Of Apoptotic Process Hindgut Morphogenesis Dendritic Spine Morphogenesis Synaptic Vesicle Maturation Insulin Metabolic Process Maintenance Of Cell Polarity Regulation Of Cell Death Hindgut Development Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Vocalization Behavior Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Glycoprotein Biosynthetic Process Generation Of Precursor Metabolites And Energy Organelle Localization Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Dendritic Spine Development Protein Localization To Synapse Positive Regulation Of Gluconeogenesis Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Triglyceride Biosynthetic Process Genitalia Morphogenesis Apoptotic DNA Fragmentation Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Dendritic Spine Organization Cellular Component Assembly
Tagcloud ?			abcc3 agilent ankrd46 begins bonferroni c1orf9 c6orf62 cd47 chernobyl david fallout fgfr1op2 frozen hey2 hnrnph1 hybridised iodine kruskal multistep panther purposes qrt representation scel serpina1 ucp3 ukrainian unirradiated wallis
Tagcloud (Difference) ?			abcc3 agilent ankrd46 begins bonferroni c1orf9 c6orf62 cd47 chernobyl david fallout fgfr1op2 frozen hey2 hnrnph1 hybridised iodine kruskal multistep panther purposes qrt representation scel serpina1 ucp3 ukrainian unirradiated wallis
Tagcloud (Intersection) ?