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TCHP and KRT5
Number of citations of the paper that reports this interaction (PubMedID
15731015
)
0
Data Source:
HPRD
(two hybrid)
TCHP
KRT5
Description
trichoplein keratin filament binding
keratin 5
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Centrosome
Cytosol
Cytoskeleton
Plasma Membrane
Cilium
Membrane
Desmosome
Nuclear Membrane
Ciliary Basal Body
Keratin Filament
Apical Cortex
Anchoring Junction
Polymeric Cytoskeletal Fiber
Nucleus
Cytoplasm
Cytosol
Intermediate Filament
Membrane
Keratin Filament
Extracellular Exosome
Molecular Function
Protein Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Structural Constituent Of Skin Epidermis
Scaffold Protein Binding
Biological Process
Apoptotic Process
Cell Projection Organization
Negative Regulation Of Cell Growth
Negative Regulation Of Cilium Assembly
Epidermis Development
Response To Mechanical Stimulus
Regulation Of Cell Migration
Keratinization
Regulation Of Protein Localization
Intermediate Filament Polymerization
Intermediate Filament Organization
Pathways
Type I hemidesmosome assembly
Keratinization
Formation of the cornified envelope
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Developmental Lineage of Mammary Gland Luminal Epithelial Cells
Developmental Lineage of Mammary Gland Myoepithelial Cells
Developmental Lineage of Mammary Stem Cells
Drugs
Zinc
Zinc acetate
Diseases
Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
Dowling-Degos disease
GWAS
Bipolar disorder (
31043756
)
Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia (
28922980
)
Metabolite levels (MHPG) (
23319000
)
Myocardial infarction (
30226566
)
Platelet count (
32888494
)
Pulse pressure (
27841878
)
Systolic blood pressure (
27841878
)
Basal cell carcinoma (
24403052
25855136
27539887
31174203
33549134
)
Cutaneous squamous cell carcinoma (
32041948
)
Keratinocyte cancer (MTAG) (
31174203
)
Non-melanoma skin cancer (
29739929
)
Squamous cell carcinoma (
31174203
)
Interacting Genes
52 interacting genes:
ATPAF2
BCAS2
C21orf91
CBY2
CCDC125
CCDC13
CCDC172
CCDC85B
CDR2
CDR2L
DMAP1
DYDC1
EIF4ENIF1
HOOK2
ID2
IFFO1
IKZF3
KCTD17
KIAA0753
KRT14
KRT15
KRT16
KRT18
KRT19
KRT24
KRT32
KRT34
KRT35
KRT40
KRT5
KRT6A
KRT75
KRT8
MIIP
MIPOL1
MKRN3
MTUS2
NAB2
NDOR1
NME7
NUP54
PRDM16
PSMB5
RABGEF1
RUSC1
TEX11
TRIM27
TRIM54
USHBP1
VIM
WWOX
ZIM2
30 interacting genes:
ALOX12
ALOX12B
APC
DSP
DST
EVPL
INCA1
KIFC3
KRT1
KRT13
KRT14
KRT15
KRT18
KRT24
KRT25
KRT27
KRT28
KRT31
KRT32
KRT33B
KRT34
KRT35
KRT36
KRT37
KRT38
KRT40
PKP2
RNF26
TCHP
UBE3A
Entrez ID
84260
3852
HPRD ID
14403
01010
Ensembl ID
ENSG00000139437
ENSG00000186081
Uniprot IDs
Q9BT92
P13647
PDB IDs
3TNU
6JFV
Enriched GO Terms of Interacting Partners
?
Intermediate Filament
Intermediate Filament Cytoskeleton Organization
Keratin Filament
Intermediate Filament-based Process
Intermediate Filament Organization
Structural Constituent Of Skin Epidermis
Supramolecular Fiber Organization
Structural Molecule Activity
Cytoskeleton Organization
Cytoskeleton
Structural Constituent Of Cytoskeleton
Morphogenesis Of An Epithelium
Epithelial Cell Differentiation
Tissue Morphogenesis
Cell Differentiation
Cellular Developmental Process
Organelle Organization
Protein Binding
Scaffold Protein Binding
Epidermis Development
Cytosol
Keratinization
Keratin Filament Binding
Cell Periphery
Developmental Process
Anatomical Structure Morphogenesis
Intermediate Filament Cytoskeleton
Nuclear Matrix
Cornified Envelope
Hair Cycle
Centrosome
Hepatocyte Apoptotic Process
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Intermediate Filament Organization
Intermediate Filament
Structural Constituent Of Skin Epidermis
Keratin Filament
Structural Molecule Activity
Supramolecular Fiber Organization
Cytoskeleton Organization
Tissue Morphogenesis
Epithelial Cell Differentiation
Morphogenesis Of An Epithelium
Cytoskeleton
Organelle Organization
Extracellular Exosome
Cytosol
Anatomical Structure Morphogenesis
Epidermis Development
Intermediate Filament Cytoskeleton
Developmental Process
Keratinization
Cellular Developmental Process
Cell Differentiation
Structural Constituent Of Cytoskeleton
Cornified Envelope
Tissue Development
Desmosome
Hair Cycle
Peptide Cross-linking
Arachidonate 12(S)-lipoxygenase Activity
Wound Healing
Anchoring Junction
Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Hair Follicle Morphogenesis
Adherens Junction
Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
Establishment Of Skin Barrier
Hepoxilin Biosynthetic Process
Polymeric Cytoskeletal Fiber
Cardiac Muscle Cell-cardiac Muscle Cell Adhesion
Skin Epidermis Development
Intermediate Filament Bundle Assembly
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Lipoxygenase Pathway
Negative Regulation Of Cyclin-dependent Protein Kinase Activity
Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen
Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Keratinocyte Differentiation
Desmosome Organization
Scaffold Protein Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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