TCHP and KRT5

Number of citations of the paper that reports this interaction (PMID 15731015)
2

Data Source:
HPRD (two hybrid)

		TCHP	KRT5
Gene Name		trichoplein, keratin filament binding	keratin 5, type II
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Plasma Membrane Keratin Filament Apical Cortex	Nucleus Cytoplasm Mitochondrion Cytosol Intermediate Filament Plasma Membrane Membrane Keratin Filament Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Growth	Epidermis Development Hemidesmosome Assembly Cell Junction Assembly
Pathways			Cell junction organization Type I hemidesmosome assembly
Drugs
Diseases
GWAS		Metabolite levels (MHPG) ( 23319000)
Protein-Protein Interactions		21 interactors: CCDC172 CCDC85B CDR2 DYDC1 KRT14 KRT15 KRT16 KRT18 KRT40 KRT5 KRT6A KRT8 LZTS2 MIPOL1 MKRN3 NAB2 NDOR1 NME7 TEX11 TRIM27 VIM	19 interactors: ALOX12 ALOX12B APC DSP DST EVPL KIFC3 KRT1 KRT14 KRT15 KRT18 KRT31 KRT38 KRT40 PKP2 SUMO1 SUMO2 SUMO3 TCHP
Entrez ID		84260	3852
HPRD ID		14403	01010
Ensembl ID		ENSG00000139437	ENSG00000186081
Uniprot IDs		Q9BT92	P13647
PDB IDs			3TNU
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Developmental Process Cytoskeleton Organization Anatomical Structure Development Epidermis Development Hemidesmosome Assembly Epithelium Development Organelle Organization Hepatocyte Apoptotic Process Intermediate Filament Organization Cellular Component Assembly Tumor Necrosis Factor-mediated Signaling Pathway Response To Zinc Ion Cell-substrate Junction Assembly Tissue Development Golgi To Plasma Membrane CFTR Protein Transport Cellular Response To Menadione Negative Regulation Of Interleukin-2 Secretion Organ Development Cellular Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Hair Cycle Meiotic Gene Conversion Response To Tumor Necrosis Factor Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Response To Inorganic Substance Negative Regulation Of Calcium Ion Import Male Meiosis Chromosome Segregation Intermediate Filament Bundle Assembly Cell Differentiation Response To Ionizing Radiation Cell Death Death Keratinocyte Migration Negative Regulation Of Transcription From RNA Polymerase III Promoter Epithelial Cell Differentiation Response To Hydrostatic Pressure Bergmann Glial Cell Differentiation Viral Process Interferon-gamma Secretion Chiasma Assembly	Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Skin Development Epidermis Development Establishment Of Skin Barrier Intermediate Filament Organization Regulation Of Water Loss Via Skin Protein Sumoylation Multicellular Organismal Water Homeostasis Hepoxilin Metabolic Process Hepoxilin Biosynthetic Process Intermediate Filament Bundle Assembly Cell Junction Assembly Water Homeostasis Bundle Of His Cell To Purkinje Myocyte Communication Anatomical Structure Development Cell-cell Junction Organization Positive Regulation Of Protein Catabolic Process Linoleic Acid Metabolic Process Desmosome Organization Hemidesmosome Assembly Lipoxygenase Pathway Developmental Process Positive Regulation Of Proteolysis Epithelium Development Long-chain Fatty Acid Biosynthetic Process Regulation Of Proteolysis Cytoskeleton Organization Ventricular Cardiac Muscle Cell Action Potential Tissue Development Regulation Of Heart Rate By Cardiac Conduction Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cellular Component Maintenance Positive Regulation Of Cellular Protein Catabolic Process Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Regulation Of Proteasomal Protein Catabolic Process Post-translational Protein Modification Single Organismal Cell-cell Adhesion Apoptotic Process Regulation Of Cardiac Muscle Cell Contraction Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Conduction Peptide Cross-linking Programmed Cell Death Cell-substrate Junction Assembly Cell Death Death
Tagcloud ?			aldh1 ciliated columnar exposes foxj1 gynaecological hgsc hgscs krt7 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns
Tagcloud (Difference) ?			aldh1 ciliated columnar exposes foxj1 gynaecological hgsc hgscs krt7 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns
Tagcloud (Intersection) ?