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TCHP and KRT18
Number of citations of the paper that reports this interaction (PMID
15731014
)
16
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
TCHP
KRT18
Gene Name
trichoplein, keratin filament binding
keratin 18, type I
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Mitochondrion
Centrosome
Plasma Membrane
Keratin Filament
Apical Cortex
Nucleolus
Cytoplasm
Microtubule Organizing Center
Intermediate Filament
Centriolar Satellite
Keratin Filament
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Cell Periphery
Molecular Function
Protein Binding
Structural Molecule Activity
Protein Binding
Poly(A) RNA Binding
Scaffold Protein Binding
Biological Process
Apoptotic Process
Negative Regulation Of Cell Growth
Cell Cycle
Anatomical Structure Morphogenesis
Viral Process
Tumor Necrosis Factor-mediated Signaling Pathway
Golgi To Plasma Membrane CFTR Protein Transport
Negative Regulation Of Apoptotic Process
Intermediate Filament Cytoskeleton Organization
Extrinsic Apoptotic Signaling Pathway
Hepatocyte Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Metabolite levels (MHPG) (
23319000
)
Protein-Protein Interactions
21 interactors:
CCDC172
CCDC85B
CDR2
DYDC1
KRT14
KRT15
KRT16
KRT18
KRT40
KRT5
KRT6A
KRT8
LZTS2
MIPOL1
MKRN3
NAB2
NDOR1
NME7
TEX11
TRIM27
VIM
73 interactors:
BBS1
BBS2
BBS4
BBS7
CAMK2A
CASP3
CASP6
CASP7
CASP8
CBL
CCDC146
CCDC85B
CCNI
CDC5L
CDK1
COL17A1
DEDD
DNAJB6
EGFR
EP300
EXOC8
FRAT1
GIT2
GOLGA2
GRN
HAUS1
HGS
HRAS
HSPA1A
HSPA4
HSPA5
IKBKG
KPNA2
KRT15
KRT5
KRT72
KRT8
LDOC1
MAPK14
NME7
ORC5
PDE4DIP
PIAS4
PKD1
PKP2
PKP3
PNN
POT1
PRKCA
PRKCE
RAF1
RHPN2
RPS6KA3
SERPINE1
SHC1
SMARCD1
SUMO1
SVIL
TCHP
TNFRSF1B
TRADD
TUBG1
TUBGCP4
TXN2
TXNDC11
UPF2
USH2A
YTHDC1
YWHAB
YWHAE
YWHAG
YWHAH
YWHAZ
Entrez ID
84260
3875
HPRD ID
14403
01020
Ensembl ID
ENSG00000139437
ENSG00000111057
Uniprot IDs
Q9BT92
P05783
PDB IDs
Enriched GO Terms of Interacting Partners
?
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Developmental Process
Cytoskeleton Organization
Anatomical Structure Development
Epidermis Development
Hemidesmosome Assembly
Epithelium Development
Organelle Organization
Hepatocyte Apoptotic Process
Intermediate Filament Organization
Cellular Component Assembly
Tumor Necrosis Factor-mediated Signaling Pathway
Response To Zinc Ion
Cell-substrate Junction Assembly
Tissue Development
Golgi To Plasma Membrane CFTR Protein Transport
Cellular Response To Menadione
Negative Regulation Of Interleukin-2 Secretion
Organ Development
Cellular Response To Tumor Necrosis Factor
Extrinsic Apoptotic Signaling Pathway
Hair Cycle
Meiotic Gene Conversion
Response To Tumor Necrosis Factor
Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway
Response To Inorganic Substance
Negative Regulation Of Calcium Ion Import
Male Meiosis Chromosome Segregation
Intermediate Filament Bundle Assembly
Cell Differentiation
Response To Ionizing Radiation
Cell Death
Death
Keratinocyte Migration
Negative Regulation Of Transcription From RNA Polymerase III Promoter
Epithelial Cell Differentiation
Response To Hydrostatic Pressure
Bergmann Glial Cell Differentiation
Viral Process
Interferon-gamma Secretion
Chiasma Assembly
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cell Death
Regulation Of Protein Metabolic Process
Cellular Response To Organic Substance
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Apoptotic Process
Neurotrophin Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Response To Organic Substance
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Cell Surface Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
ERBB Signaling Pathway
Cellular Component Assembly
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cell Communication
Positive Regulation Of Cellular Protein Metabolic Process
Membrane Organization
Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Signaling
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Organelle Organization
Innate Immune Response
Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Signal Transduction
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Transport
Anatomical Structure Development
Mitotic Cell Cycle
Regulation Of Cellular Component Organization
Regulation Of Signaling
Mitotic Cell Cycle Phase Transition
Cellular Response To Fibroblast Growth Factor Stimulus
Cell Cycle Phase Transition
Enzyme Linked Receptor Protein Signaling Pathway
Response To Fibroblast Growth Factor
Developmental Process
Defense Response
Regulation Of Proteolysis
Cellular Protein Localization
Cellular Response To Stimulus
Tagcloud
?
actg2
adenomatous
archived
b4ganlt2
bank
casp3
cdx1
cdx2
classifier
cnn1
col1a1
custom
ezr
fsp1
genomelab
hcellmarkerplex
house
hybridisation
incorporates
lgr5
ms4a12
muc2
mucin
nox1
ntn1
polyp
signatures
slc9a2
vwf
Tagcloud (Difference)
?
actg2
adenomatous
archived
b4ganlt2
bank
casp3
cdx1
cdx2
classifier
cnn1
col1a1
custom
ezr
fsp1
genomelab
hcellmarkerplex
house
hybridisation
incorporates
lgr5
ms4a12
muc2
mucin
nox1
ntn1
polyp
signatures
slc9a2
vwf
Tagcloud (Intersection)
?