TMOD2 and TPM3

Number of citations of the paper that reports this interaction (PMID 8886980)
14

Data Source:
HPRD (in vitro)

		TMOD2	TPM3
Gene Name		tropomodulin 2 (neuronal)	tropomyosin 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Striated Muscle Thin Filament Growth Cone	Stress Fiber Podosome Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Growth Cone Cortical Cytoskeleton Filamentous Actin Cleavage Furrow Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Tropomyosin Binding	Molecular_function Actin Binding
	Biological Process	Muscle Contraction Actin Filament Organization Neuron-neuron Synaptic Transmission Nervous System Development Learning Or Memory Myofibril Assembly Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Pointed-end Actin Filament Capping	Movement Of Cell Or Subcellular Component Muscle Contraction Muscle Filament Sliding
Pathways			Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: APP TPM1 TPM3	41 interactors: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 FAM9C FBXO5 HDDC3 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P
Entrez ID		29767	7170
HPRD ID		04237	01840
Ensembl ID		ENSG00000128872	ENSG00000143549
Uniprot IDs		Q9NZR1	B4DQ80 P06753 Q5VU58 Q5VU63 Q8TCG3
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Positive Regulation Of Heart Rate By Epinephrine Synaptic Growth At Neuromuscular Junction Muscle Contraction Movement Of Cell Or Subcellular Component Collateral Sprouting In Absence Of Injury Muscle System Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Response To Oxidative Stress Regulation Of Heart Rate By Chemical Signal Neuron Remodeling Wound Healing Actin Filament-based Process Cellular Copper Ion Homeostasis Response To Wounding Positive Regulation Of Heart Rate Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Heart Contraction Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of ATPase Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Ruffle Organization Positive Regulation Of Blood Pressure Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of ATPase Activity Ventricular Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Hydrolase Activity Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Stress Fiber Assembly Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Actin Filament Bundle Assembly Cardiac Muscle Contraction Axon Cargo Transport Mating Neuromuscular Junction Development	Actomyosin Structure Organization Organelle Organization Actin Filament-based Process Regulation Of Organelle Organization Cellular Component Assembly Actin-myosin Filament Sliding Muscle Filament Sliding Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Cytoskeleton Organization Actin-mediated Cell Contraction Regulation Of Cytoskeleton Organization Actin Filament Organization Actin Filament-based Movement Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Pointed-end Actin Filament Capping Regulation Of Chromosome Segregation Regulation Of Actin Polymerization Or Depolymerization Myofibril Assembly Regulation Of Actin Filament Length Cell-cell Junction Organization Regulation Of Mitotic Cell Cycle Muscle Contraction Cell Division Cell Cycle Muscle System Process Organelle Assembly Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Cell Development Movement Of Cell Or Subcellular Component Mitotic Nuclear Division Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Cellular Component Organization Regulation Of Muscle Contraction Positive Regulation Of Transcription Factor Import Into Nucleus Striated Muscle Cell Development Negative Regulation Of Centriole-centriole Cohesion Positive Regulation Of Transforming Growth Factor Beta3 Production Inhibition Of APC-Cdc20 Complex Activity Regulation Of Metaphase Plate Congression Posterior Compartment Specification Anterior Compartment Pattern Formation Negative Regulation Of Cytoskeleton Organization Regulation Of Mitotic Sister Chromatid Separation Arp2/3 Complex-mediated Actin Nucleation Muscle Cell Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Tagcloud ?			aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc
Tagcloud (Difference) ?			aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc
Tagcloud (Intersection) ?