TMOD2

Description		tropomodulin 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Striated Muscle Thin Filament Myofibril Synapse
	Molecular Function	Actin Binding Protein Binding Tropomyosin Binding
	Biological Process	Muscle Contraction Actin Filament Organization Neuron-neuron Synaptic Transmission Nervous System Development Learning Or Memory Myofibril Assembly Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Pointed-end Actin Filament Capping
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS		Adult body size ( 32376654) Intelligence (MTAG) ( 29326435)
Interacting Genes		4 interacting genes: APP FBXO7 TPM1 TPM3
Entrez ID		29767
HPRD ID		04237
Ensembl ID		ENSG00000128872
Uniprot IDs		Q9NZR1
PDB IDs
Enriched GO Terms of Interacting Partners?		Muscle Thin Filament Tropomyosin Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Heterodimerization Activity Supramolecular Fiber Organization Actin Filament Positive Regulation Of Heart Rate By Epinephrine Stress Fiber Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Lewy Body Core Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Locomotion Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Actin Filament Binding Muscle Contraction Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Heart Rate By Chemical Signal Regulation Of Spontaneous Synaptic Transmission Regulation Of Neuron Apoptotic Process Regulation Of Blood Circulation NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway
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