Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
GRIN2D and DLGAP4
Number of citations of the paper that reports this interaction (PMID
10862698
)
203
Data Source:
HPRD
(in vivo)
GRIN2D
DLGAP4
Gene Name
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
discs, large (Drosophila) homolog-associated protein 4
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
N-methyl-D-aspartate Selective Glutamate Receptor Complex
Cell Junction
Dendrite
Postsynaptic Membrane
Membrane
Synapse
Molecular Function
N-methyl-D-aspartate Selective Glutamate Receptor Activity
Extracellular-glutamate-gated Ion Channel Activity
Protein Binding
Protein Binding
Biological Process
Startle Response
Signal Transduction
Synaptic Transmission
Adult Locomotory Behavior
Ion Transmembrane Transport
Ionotropic Glutamate Receptor Signaling Pathway
Synaptic Transmission, Glutamatergic
Regulation Of Sensory Perception Of Pain
Cell-cell Signaling
Pathways
Activation of NMDA receptor upon glutamate binding and postsynaptic events
CREB phosphorylation through the activation of CaMKII
CREB phosphorylation through the activation of Ras
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Unblocking of NMDA receptor, glutamate binding and activation
Ras activation uopn Ca2+ infux through NMDA receptor
Post NMDA receptor activation events
Transmission across Chemical Synapses
Drugs
L-Glutamic Acid
Meperidine
Orphenadrine
Tenocyclidine
Diseases
GWAS
Protein-Protein Interactions
33 interactors:
ABL1
CDH2
CIT
CLTC
CTNNB1
DLG2
DLG4
DLGAP4
DNM1
DUSP4
FUS
GRIN1
HNRNPU
HRAS
HSPA1A
IL16
INA
INADL
MAP2
MAP2K2
NANOS1
NF1
PPP2R1A
PPP2R2A
PRKCB
PRKCE
PRKCG
RAP2A
RPS6KA3
SPTAN1
SYNGAP1
TJP1
TRAF3
15 interactors:
BIN1
DLG1
DLG3
DLG4
EXOC4
GRIN1
GRIN2D
PLP2
PPP1R1B
SH3GL2
SHANK2
SHANK3
SORBS2
SYNGAP1
UBC
Entrez ID
2906
22839
HPRD ID
04095
16826
Ensembl ID
ENSG00000105464
ENSG00000080845
Uniprot IDs
O15399
Q59G17
Q9Y2H0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nervous System Development
Regulation Of MAPK Cascade
Regulation Of Long-term Neuronal Synaptic Plasticity
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurogenesis
Cell Development
Locomotion
Generation Of Neurons
Intracellular Signal Transduction
Neuron Projection Development
Cell Differentiation
Regulation Of Cellular Component Organization
Regulation Of Neuronal Synaptic Plasticity
Cellular Response To Stimulus
Neuron Differentiation
Enzyme Linked Receptor Protein Signaling Pathway
Cell Projection Organization
Signaling
Cell Morphogenesis Involved In Differentiation
Axonogenesis
MyD88-independent Toll-like Receptor Signaling Pathway
Neuron Development
Cell Communication
Apoptotic Process
Response To Organic Substance
Signal Transduction
Axon Guidance
Axon Development
Programmed Cell Death
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Cell Death
Toll-like Receptor 4 Signaling Pathway
Death
Regulation Of Neuron Death
Developmental Process
Neuron Projection Morphogenesis
Response To Ammonium Ion
Immune Response-regulating Signaling Pathway
Regulation Of Metabolic Process
Response To Stimulus
Response To Morphine
Regulation Of Intracellular Signal Transduction
Cell-cell Signaling
Regulation Of Phosphorus Metabolic Process
Movement Of Cell Or Subcellular Component
Multicellular Organismal Development
Response To External Stimulus
Toll-like Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Receptor Clustering
Learning
Regulation Of Long-term Neuronal Synaptic Plasticity
Single-organism Behavior
Social Behavior
Learning Or Memory
Receptor Localization To Synapse
Membrane Organization
Cognition
Synaptic Transmission
Behavior
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Synaptic Plasticity
Vocalization Behavior
Protein Localization To Synapse
Neuron Projection Development
Cell-cell Signaling
Establishment Or Maintenance Of Apical/basal Cell Polarity
Neuron Development
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Synaptic Transmission
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Chemotaxis
Generation Of Neurons
Neuron Projection Morphogenesis
Nervous System Development
Protein Localization To Membrane
Positive Regulation Of Membrane Potential
Neurogenesis
Neuron Differentiation
Cell Projection Organization
Neurological System Process
Cell Morphogenesis Involved In Differentiation
Axon Guidance
Adult Behavior
Response To External Stimulus
Locomotion
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering
Nucleotide Phosphorylation
Cell Projection Morphogenesis
Visual Learning
Cell Part Morphogenesis
Visual Behavior
Regulation Of Excitatory Postsynaptic Membrane Potential
Axonogenesis
Regulation Of Postsynaptic Membrane Potential
Synapse Assembly
Axon Development
Associative Learning
Regulation Of Membrane Potential
Tagcloud
?
6j
6jxm
atg
autosomes
backcross
codon
crosses
dispersed
egr
epsilon
espilon
exons
f1xc57bl
flanking
grinl
interspecific
mapping
nucleas
polyadenylation
primer
s1
spans
spl
spretus
termination
zeta
Tagcloud (Difference)
?
6j
6jxm
atg
autosomes
backcross
codon
crosses
dispersed
egr
epsilon
espilon
exons
f1xc57bl
flanking
grinl
interspecific
mapping
nucleas
polyadenylation
primer
s1
spans
spl
spretus
termination
zeta
Tagcloud (Intersection)
?