DLGAP4 and PPP1R1B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLGAP4	PPP1R1B
Description		DLG associated protein 4	protein phosphatase 1 regulatory inhibitor subunit 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Neuromuscular Junction Synapse Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization	Nucleus Cytoplasm Cytosol Neuronal Cell Body
	Molecular Function	Protein Binding Molecular Adaptor Activity	Protein Kinase Inhibitor Activity CAMP-dependent Protein Kinase Inhibitor Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Signaling Modulation Of Chemical Synaptic Transmission Regulation Of Synapse Maturation Modification Of Postsynaptic Structure	Response To Amphetamine DNA-templated Transcription Signal Transduction Negative Regulation Of Female Receptivity Locomotory Behavior Visual Learning Intracellular Signal Transduction Response To Morphine Behavioral Response To Cocaine Cellular Response To Cocaine
Pathways		Neurexins and neuroligins Neurexins and neuroligins	DARPP-32 events DARPP-32 events
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Neuroblastoma or malignant cutaneous melanoma ( 31605138)	Asthma ( 31619474 31959851) Estimated glomerular filtration rate ( 31015462) Hematocrit ( 32888494) Hemoglobin ( 32888494) Refractive error ( 32231278) Ulcerative colitis ( 20228799)
Interacting Genes		32 interacting genes: ABI2 ALDH16A1 ATPAF2 BIN1 DLG1 DLG3 DLG4 EXOC4 FHL3 FHL5 FKBP6 FYN GRIN1 GRIN2D MAGEA6 MPP7 MTUS2 NCK1 NCK2 NHERF1 NHERF2 PALS1 PLP2 PPP1R1B SH3GL2 SH3RF1 SHANK2 SHANK3 SORBS2 SYNGAP1 UBASH3A UBC	9 interacting genes: CDK5 CSNK2A1 CSNK2A2 DLGAP4 KLHL6 PPP1CA PRKACA ROBO2 TFCP2
Entrez ID		22839	84152
HPRD ID		16826	05097
Ensembl ID		ENSG00000080845	ENSG00000131771
Uniprot IDs		A0A0B4J2C2 Q9Y2H0	B3KVQ9 Q9UD71
PDB IDs
Enriched GO Terms of Interacting Partners?		Ionotropic Glutamate Receptor Binding Postsynaptic Density Learning Receptor Clustering Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Membrane Regulation Of Neuronal Synaptic Plasticity Cytoskeletal Anchor Activity Positive Regulation Of Excitatory Postsynaptic Potential Localization Within Membrane Establishment Or Maintenance Of Cell Polarity Learning Or Memory Associative Learning Adherens Junction Postsynaptic Density Membrane Cognition Positive Regulation Of Actin Filament Polymerization Regulation Of Synaptic Plasticity Modulation Of Excitatory Postsynaptic Potential Glutamate Receptor Signaling Pathway Neuron Projection Phosphatase Binding Response To Glycine Type 2 Metabotropic Glutamate Receptor Binding Postsynaptic Density Organization Synapse Regulation Of Cellular Component Size Glutamatergic Synapse Positive Regulation Of Synaptic Transmission Vocalization Behavior Dendritic Spine Regulation Of Actin Filament Organization Scaffold Protein Binding Type 3 Metabotropic Glutamate Receptor Binding Postsynaptic Specialization Organization Signaling Adaptor Activity Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Protein Polymerization Lateral Loop Protein Localization To Cell Junction Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Synaptic Receptor Adaptor Activity Positive Regulation Of Cytoskeleton Organization Chemical Synaptic Transmission Ionotropic Glutamate Receptor Signaling Pathway Regulation Of Biological Quality Plasma Membrane MPP7-DLG1-LIN7 Complex	Protein Kinase CK2 Complex Regulation Of Macroautophagy Neuromuscular Junction Protein Serine Kinase Activity Regulation Of Proteolysis Regulation Of Autophagy Regulation Of Protein Catabolic Process Protein Serine/threonine Kinase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Proteolysis Regulation Of Cell Communication Regulation Of Signaling PcG Protein Complex Modulation Of Chemical Synaptic Transmission Protein Kinase Activity Macromolecule Catabolic Process Regulation Of Protein Export From Nucleus Regulation Of Proteasomal Protein Catabolic Process Glutamatergic Synapse Presynapse Hsp90 Protein Binding Kinase Activity Central Nervous System Neuron Development Protein Catabolic Process Double-strand Break Repair Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Glucose Metabolic Process Rhythmic Process Regulation Of Synaptic Vesicle Exocytosis Regulation Of Synapse Organization Negative Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Presynaptic Cytosolic Calcium Concentration Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Protein Catabolic Process At Presynapse, Modulating Synaptic Transmission Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Establishment Of Protein Localization Anatomical Structure Formation Involved In Morphogenesis Regulation Of Chromosome Separation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Macromolecule Metabolic Process Acetylcholine Receptor Activator Activity Regulation Of Cellular Component Organization Regulation Of Neurotransmitter Secretion Cerebral Cortex Development Negative Regulation Of Catabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Apoptotic Process Regulation Of Apoptotic Signaling Pathway
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