DLGAP4 and PPP1R1B

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLGAP4	PPP1R1B
Gene Name		discs, large (Drosophila) homolog-associated protein 4	protein phosphatase 1, regulatory (inhibitor) subunit 1B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Synapse	Nucleus Cytoplasm Cytosol Neuronal Cell Body
	Molecular Function	Protein Binding	Protein Kinase Inhibitor Activity Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Phosphatase Type 1 Regulator Activity D1 Dopamine Receptor Binding D2 Dopamine Receptor Binding D3 Dopamine Receptor Binding D4 Dopamine Receptor Binding D5 Dopamine Receptor Binding
	Biological Process	Cell-cell Signaling	Response To Amphetamine Transcription, DNA-templated Negative Regulation Of Protein Kinase Activity Signal Transduction Negative Regulation Of Female Receptivity Visual Learning Intracellular Signal Transduction Negative Regulation Of Catalytic Activity Regulation Of Catalytic Activity
Pathways			Signaling by GPCR Opioid Signalling DARPP-32 events
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: BIN1 DLG1 DLG3 DLG4 EXOC4 GRIN1 GRIN2D PLP2 PPP1R1B SH3GL2 SHANK2 SHANK3 SORBS2 SYNGAP1 UBC	9 interactors: CDK5 CSNK2A1 CSNK2A2 DLGAP4 KLHL6 PPP1CA PRKACA ROBO2 TFCP2
Entrez ID		22839	84152
HPRD ID		16826	05097
Ensembl ID		ENSG00000080845	ENSG00000131771
Uniprot IDs		Q9Y2H0	B3KVQ9 Q9UD71
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Clustering Learning Regulation Of Long-term Neuronal Synaptic Plasticity Single-organism Behavior Social Behavior Learning Or Memory Receptor Localization To Synapse Membrane Organization Cognition Synaptic Transmission Behavior Regulation Of Neuronal Synaptic Plasticity Regulation Of Synaptic Plasticity Vocalization Behavior Protein Localization To Synapse Neuron Projection Development Cell-cell Signaling Establishment Or Maintenance Of Apical/basal Cell Polarity Neuron Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Synaptic Transmission Positive Regulation Of Excitatory Postsynaptic Membrane Potential Chemotaxis Generation Of Neurons Neuron Projection Morphogenesis Nervous System Development Protein Localization To Membrane Positive Regulation Of Membrane Potential Neurogenesis Neuron Differentiation Cell Projection Organization Neurological System Process Cell Morphogenesis Involved In Differentiation Axon Guidance Adult Behavior Response To External Stimulus Locomotion Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Nucleotide Phosphorylation Cell Projection Morphogenesis Visual Learning Cell Part Morphogenesis Visual Behavior Regulation Of Excitatory Postsynaptic Membrane Potential Axonogenesis Regulation Of Postsynaptic Membrane Potential Synapse Assembly Axon Development Associative Learning Regulation Of Membrane Potential	Chemotaxis Rhythmic Process Axon Guidance Regulation Of Protein Processing Apoptotic Process Response To External Stimulus Programmed Cell Death Cell Death Death Regulation Of Cell Cycle Process Triglyceride Catabolic Process Axonogenesis Axon Development Acylglycerol Catabolic Process Cell Morphogenesis Involved In Neuron Differentiation Locomotion Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Export From Nucleus Neuron Projection Morphogenesis Cell Cycle Regulation Of Proteolysis Anatomical Structure Morphogenesis Signaling Cell Communication Cell Morphogenesis Involved In Differentiation Mitotic Spindle Checkpoint Movement Of Cell Or Subcellular Component Negative Regulation Of Chromosome Segregation Peptidyl-threonine Phosphorylation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Cellular Protein Metabolic Process Neuron Projection Development Regulation Of Mitotic Metaphase/anaphase Transition Cell Projection Morphogenesis Cell Part Morphogenesis Negative Regulation Of Protein Metabolic Process Response To Light Stimulus Regulation Of Cell Cycle Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Development Negative Regulation Of Proteolysis Negative Regulation Of Proteasomal Protein Catabolic Process Neuron Development Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Dense Core Granule Biogenesis
Tagcloud ?			17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis ikzf3 immumohistochemical implied per1 perld1 q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?			17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis ikzf3 immumohistochemical implied per1 perld1 q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?