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DLGAP4 and BIN1
Number of citations of the paper that reports this interaction (PMID
16275660
)
13
Data Source:
BioGRID
(unspecified method, pull down, two hybrid)
HPRD
(in vitro, two hybrid, in vivo)
DLGAP4
BIN1
Gene Name
discs, large (Drosophila) homolog-associated protein 4
bridging integrator 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Membrane
Synapse
Nucleus
Cytoplasm
Synaptic Vesicle
Actin Cytoskeleton
Membrane
Z Disc
T-tubule
Axon
I Band
Node Of Ranvier
Axon Initial Segment
Varicosity
Axon Terminus
Cerebellar Mossy Fiber
Lipid Tube
Molecular Function
Protein Binding
Protein Binding
Protein Complex Binding
Identical Protein Binding
Protein Heterodimerization Activity
Tau Protein Binding
GTPase Binding
RNA Polymerase Binding
Biological Process
Cell-cell Signaling
Endocytosis
Cell Proliferation
Viral Process
Muscle Cell Differentiation
Positive Regulation Of Apoptotic Process
Positive Regulation Of GTPase Activity
Regulation Of Neuron Differentiation
Positive Regulation Of Endocytosis
Positive Regulation Of Astrocyte Differentiation
Lipid Tube Assembly
Regulation Of Cell Cycle Arrest
Pathways
Drugs
Diseases
GWAS
Alzheimer's disease (
22832961
21460840
21627779
22005930
)
Alzheimer's disease (late onset) (
21460841
21390209
)
Protein-Protein Interactions
15 interactors:
BIN1
DLG1
DLG3
DLG4
EXOC4
GRIN1
GRIN2D
PLP2
PPP1R1B
SH3GL2
SHANK2
SHANK3
SORBS2
SYNGAP1
UBC
36 interactors:
ABL1
AMPH
AP2A1
AP2A2
APP
ASAP2
ATXN2
CUX1
DLGAP4
DNM1
DNM2
FBP1
ITGA1
ITGA3
ITGA6
MAP4K3
MBNL1
MYC
PLD1
PLD2
PTK2
RAP1A
RFX3
RIN2
RIN3
SH3GL2
SH3GLB1
SNX4
SOS1
SOS2
SYN1
SYNJ1
TP73
UBC
XRCC4
ZBTB3
Entrez ID
22839
274
HPRD ID
16826
03150
Ensembl ID
ENSG00000080845
ENSG00000136717
Uniprot IDs
Q9Y2H0
B7Z6Y2
O00499
Q9BTH3
PDB IDs
1MUZ
1MV0
1MV3
2FIC
2RMY
2RND
Enriched GO Terms of Interacting Partners
?
Receptor Clustering
Learning
Regulation Of Long-term Neuronal Synaptic Plasticity
Single-organism Behavior
Social Behavior
Learning Or Memory
Receptor Localization To Synapse
Membrane Organization
Cognition
Synaptic Transmission
Behavior
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Synaptic Plasticity
Vocalization Behavior
Protein Localization To Synapse
Neuron Projection Development
Cell-cell Signaling
Establishment Or Maintenance Of Apical/basal Cell Polarity
Neuron Development
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Synaptic Transmission
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Chemotaxis
Generation Of Neurons
Neuron Projection Morphogenesis
Nervous System Development
Protein Localization To Membrane
Positive Regulation Of Membrane Potential
Neurogenesis
Neuron Differentiation
Cell Projection Organization
Neurological System Process
Cell Morphogenesis Involved In Differentiation
Axon Guidance
Adult Behavior
Response To External Stimulus
Locomotion
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering
Nucleotide Phosphorylation
Cell Projection Morphogenesis
Visual Learning
Cell Part Morphogenesis
Visual Behavior
Regulation Of Excitatory Postsynaptic Membrane Potential
Axonogenesis
Regulation Of Postsynaptic Membrane Potential
Synapse Assembly
Axon Development
Associative Learning
Regulation Of Membrane Potential
Regulation Of Signaling
Endocytosis
Generation Of Neurons
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Projection Organization
Regulation Of ERBB Signaling Pathway
Neurogenesis
Neuron Projection Morphogenesis
Cell Projection Morphogenesis
Cell Part Morphogenesis
Regulation Of Signal Transduction
Axon Guidance
Neuron Differentiation
Neuron Development
Nervous System Development
Vesicle-mediated Transport
Chemotaxis
Signaling
Neuron Projection Development
Locomotion
Cell Communication
Anatomical Structure Morphogenesis
Cell Morphogenesis
Axonogenesis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Axon Development
Negative Regulation Of Signaling
Cell Differentiation
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Morphogenesis Involved In Neuron Differentiation
Negative Regulation Of ERBB Signaling Pathway
Regulation Of Cellular Process
Cell Development
Positive Regulation Of Catalytic Activity
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurotrophin Signaling Pathway
System Development
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Metabolic Process
Cell Morphogenesis Involved In Differentiation
Regulation Of Catalytic Activity
Regulation Of Intracellular Signal Transduction
Movement Of Cell Or Subcellular Component
Cellular Response To Growth Factor Stimulus
Regulation Of Body Fluid Levels
Positive Regulation Of Apoptotic Process
Blood Coagulation
Tagcloud
?
a2m
algorithm
allele
alzheimer
amplicons
apoe
apoj
biochip
clut
combinations
cr1
determina
e3
e4
epsilon2
epsilon4
exoc3l2
gab2
genotyping
immobilized
microchip
oligonucleotides
picalm
predis
rs11136000
sporadic
studying
tion
tomm40
Tagcloud (Difference)
?
a2m
algorithm
allele
alzheimer
amplicons
apoe
apoj
biochip
clut
combinations
cr1
determina
e3
e4
epsilon2
epsilon4
exoc3l2
gab2
genotyping
immobilized
microchip
oligonucleotides
picalm
predis
rs11136000
sporadic
studying
tion
tomm40
Tagcloud (Intersection)
?