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GRIN2D
Gene Name
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
N-methyl-D-aspartate Selective Glutamate Receptor Complex
Cell Junction
Dendrite
Postsynaptic Membrane
Molecular Function
N-methyl-D-aspartate Selective Glutamate Receptor Activity
Extracellular-glutamate-gated Ion Channel Activity
Protein Binding
Biological Process
Startle Response
Signal Transduction
Synaptic Transmission
Adult Locomotory Behavior
Ion Transmembrane Transport
Ionotropic Glutamate Receptor Signaling Pathway
Synaptic Transmission, Glutamatergic
Regulation Of Sensory Perception Of Pain
Pathways
Activation of NMDA receptor upon glutamate binding and postsynaptic events
CREB phosphorylation through the activation of CaMKII
CREB phosphorylation through the activation of Ras
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Unblocking of NMDA receptor, glutamate binding and activation
Ras activation uopn Ca2+ infux through NMDA receptor
Post NMDA receptor activation events
Transmission across Chemical Synapses
Drugs
L-Glutamic Acid
Meperidine
Orphenadrine
Tenocyclidine
Diseases
GWAS
Protein-protein Interactions
33 interactors:
ABL1
CDH2
CIT
CLTC
CTNNB1
DLG2
DLG4
DLGAP4
DNM1
DUSP4
FUS
GRIN1
HNRNPU
HRAS
HSPA1A
IL16
INA
INADL
MAP2
MAP2K2
NANOS1
NF1
PPP2R1A
PPP2R2A
PRKCB
PRKCE
PRKCG
RAP2A
RPS6KA3
SPTAN1
SYNGAP1
TJP1
TRAF3
Entrez ID
2906
HPRD ID
04095
Ensembl ID
ENSG00000105464
Uniprot IDs
O15399
Q59G17
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nervous System Development
Regulation Of MAPK Cascade
Regulation Of Long-term Neuronal Synaptic Plasticity
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurogenesis
Cell Development
Locomotion
Generation Of Neurons
Intracellular Signal Transduction
Neuron Projection Development
Cell Differentiation
Regulation Of Cellular Component Organization
Regulation Of Neuronal Synaptic Plasticity
Cellular Response To Stimulus
Neuron Differentiation
Enzyme Linked Receptor Protein Signaling Pathway
Cell Projection Organization
Signaling
Cell Morphogenesis Involved In Differentiation
Axonogenesis
MyD88-independent Toll-like Receptor Signaling Pathway
Neuron Development
Cell Communication
Apoptotic Process
Response To Organic Substance
Signal Transduction
Axon Guidance
Axon Development
Programmed Cell Death
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Cell Death
Toll-like Receptor 4 Signaling Pathway
Death
Regulation Of Neuron Death
Developmental Process
Neuron Projection Morphogenesis
Response To Ammonium Ion
Immune Response-regulating Signaling Pathway
Regulation Of Metabolic Process
Response To Stimulus
Response To Morphine
Regulation Of Intracellular Signal Transduction
Cell-cell Signaling
Regulation Of Phosphorus Metabolic Process
Movement Of Cell Or Subcellular Component
Multicellular Organismal Development
Response To External Stimulus
Toll-like Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Tagcloud
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6j
6jxm
atg
autosomes
backcross
codon
crosses
dispersed
egr
epsilon
espilon
exons
f1xc57bl
flanking
grinl
interspecific
mapping
nucleas
polyadenylation
primer
s1
spans
spl
spretus
termination
zeta