GRIK1 and DLST

  • Number of citations of the paper that reports this interaction (PubMedID 35914814)
  • 83
  • Data Source:
  • BioGRID (two hybrid)

GRIK1

DLST

Description glutamate ionotropic receptor kainate type subunit 1 dihydrolipoamide S-succinyltransferase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Body mass index ( 22446040)
  • Breast cancer ( 17903305)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Forehead morphology ( 29921221)
  • Generalized epilepsy ( 30531953)
  • Glucocorticoid-induced osteonecrosis ( 26265699)
  • HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
  • Hepatocellular carcinoma ( 22807686)
  • Hyperactive-impulsive symptoms ( 18821565)
  • Lung cancer ( 34062886)
  • Periodontitis (DPAL) ( 24024966)
  • Plasma parathyroid hormone levels ( 30134803)
  • Refractive error ( 32231278)
  • Response to statin therapy ( 20339536)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Appendicular lean mass ( 33097823)
  • Depression ( 29700475)
  • Eosinophil count ( 32888494)
  • Mood instability ( 29187730)
  • Non-small cell lung cancer ( 23144319)
Interacting Genes 31 interacting genes: COPS5 CYSLTR2 DLG4 DLST DNAJB9 FLNA GORASP2 GRIK2 GRIK3 GRIK4 GRIK5 GRIP1 HOMER1 HSP90B1 KALRN KCNQ2 LDB2 PICK1 PTPRD RANBP9 RNF123 SDCBP SEPTIN7 SIPA1L3 SNAPIN SRI ST13 TAAR1 UBE2O ZFC3H1 ZNF592 21 interacting genes: ARIH2 CCDC86 DLG5 FLII GRIK1 HUNK NAP1L1 NDRG1 OGDH OGT PAK4 PFN2 RUSC2 SCFD1 SIAH2 TUBB4B UMPS USP7 WEE2-AS1 ZBTB16 ZHX1
Entrez ID 2897 1743
HPRD ID 00693 00520
Ensembl ID ENSG00000171189 ENSG00000119689
Uniprot IDs B7Z256 B7Z3V7 E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086 B7Z6J1 P36957
PDB IDs 2ZNS 2ZNT 2ZNU 3FUZ 3FV1 3FV2 3FVG 3FVK 3FVN 3FVO 4MF3 6H05
Enriched GO Terms of Interacting Partners?
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