DLST and FLII

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLST	FLII
Gene Name		dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	flightless I homolog (Drosophila)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrial Matrix Membrane Oxoglutarate Dehydrogenase Complex Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Microtubule Organizing Center Focal Adhesion
	Molecular Function	Dihydrolipoyllysine-residue Succinyltransferase Activity	Actin Binding Protein Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle Lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Muscle Contraction Multicellular Organismal Development Actin Cytoskeleton Organization Actin Filament Severing
Pathways		Lysine catabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Metabolism of amino acids and derivatives Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		Non-small cell lung cancer ( 23144319)
Protein-Protein Interactions		15 interactors: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UMPS ZBTB16 ZHX1	12 interactors: ACTB ACTL6A CARM1 DLST ESR1 GRIP1 LRRFIP1 LRRFIP2 MYD88 OPTN PRMT1 TRAIP
Entrez ID		1743	2314
HPRD ID		00520	02647
Ensembl ID		ENSG00000119689	ENSG00000177731
Uniprot IDs		B7Z6J1 P36957	Q13045
PDB IDs
Enriched GO Terms of Interacting Partners?			Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Modification Signal Transduction Chromatin Organization Peptidyl-arginine N-methylation Signaling Cell Communication Histone Arginine Methylation Intracellular Estrogen Receptor Signaling Pathway Peptidyl-arginine Methylation Response To Stimulus Chromosome Organization Chromatin Remodeling Cellular Response To Stimulus Intracellular Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling ATP-dependent Chromatin Remodeling Histone H3-R17 Methylation Positive Regulation Of Type I Interferon Production Histone Modification Histone H3-R2 Methylation Cell Development Regulation Of Type I Interferon Production Prostate Epithelial Cord Elongation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Methylation Response To Molecule Of Fungal Origin Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Negative Regulation Of Receptor Recycling Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Interleukin-23 Production Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of RNA Metabolic Process Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Protein Methylation Regulation Of Growth Regulation Of Cellular Process Defense Response Golgi Ribbon Formation Establishment Of Endothelial Intestinal Barrier Regulation Of Organ Morphogenesis Defense Response To Bacterium
Tagcloud ?		acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis	a549 accessibility assisted brahma brg1 carm1 chromatin coactivator col1a2 depleted depletion drosophila enhancer faire flightless formaldehyde grip1 homolog isolation notably qpcr recruiting remodeling smad snf swi synergistic tgfbeta transforming
Tagcloud (Difference) ?		acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis	a549 accessibility assisted brahma brg1 carm1 chromatin coactivator col1a2 depleted depletion drosophila enhancer faire flightless formaldehyde grip1 homolog isolation notably qpcr recruiting remodeling smad snf swi synergistic tgfbeta transforming
Tagcloud (Intersection) ?