DLST and NAP1L1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLST	NAP1L1
Gene Name		dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	nucleosome assembly protein 1-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrial Matrix Membrane Oxoglutarate Dehydrogenase Complex Extracellular Vesicular Exosome	Nucleus Membrane Melanosome
	Molecular Function	Dihydrolipoyllysine-residue Succinyltransferase Activity	Protein Binding Poly(A) RNA Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle Lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process	DNA Replication Nucleosome Assembly Positive Regulation Of Cell Proliferation
Pathways		Lysine catabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Metabolism of amino acids and derivatives Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		Non-small cell lung cancer ( 23144319)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		15 interactors: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UMPS ZBTB16 ZHX1	14 interactors: CREBBP CSNK2B DLST EP300 FSD1 HBA1 MED10 NR2F6 PHB POT1 SP1 TERF1 TP53 TPX2
Entrez ID		1743	4673
HPRD ID		00520	01248
Ensembl ID		ENSG00000119689	ENSG00000187109
Uniprot IDs		B7Z6J1 P36957	B3KV44 B7Z4K9 B7Z9C2 F8W543 P55209
PDB IDs
Enriched GO Terms of Interacting Partners?			N-terminal Peptidyl-lysine Acetylation Mitotic Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of DNA Replication Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomerase Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation Of Macromolecule Biosynthetic Process Chromosome Organization Positive Regulation Of Cellular Biosynthetic Process Positive Regulation By Host Of Viral Transcription Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase N-terminal Protein Amino Acid Acetylation Negative Regulation Of DNA Metabolic Process Rhythmic Process Cellular Response To Hypoxia Positive Regulation Of Metabolic Process Cellular Response To Decreased Oxygen Levels Mitotic Cell Cycle Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Telomerase Activity Cellular Response To Oxygen Levels Chromatin Organization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of DNA Replication Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Telomere Maintenance Positive Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Androgen Receptor Signaling Pathway Notch Signaling Pathway Cellular Nitrogen Compound Metabolic Process RNA-dependent DNA Replication Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Cellular Metabolic Process Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Photoperiodism Entrainment Of Circadian Clock N-terminal Protein Amino Acid Modification Organelle Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Gene Expression
Tagcloud ?		acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis	arrays asf1a assembles assembly breaks caf chaperones clamp coupled elucidating faithfully h2a h2b loader nascent nucleosomal nucleosome nucleosomes p48 packaging pcna progress recapitulates replication replicative reproduces rfc strand synthesized
Tagcloud (Difference) ?		acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis	arrays asf1a assembles assembly breaks caf chaperones clamp coupled elucidating faithfully h2a h2b loader nascent nucleosomal nucleosome nucleosomes p48 packaging pcna progress recapitulates replication replicative reproduces rfc strand synthesized
Tagcloud (Intersection) ?