DLST and CCDC86

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLST	CCDC86
Gene Name		dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	coiled-coil domain containing 86
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrial Matrix Membrane Oxoglutarate Dehydrogenase Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Dihydrolipoyllysine-residue Succinyltransferase Activity	Protein Binding Poly(A) RNA Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle Lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process	Viral Process
Pathways		Lysine catabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Metabolism of amino acids and derivatives Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		Non-small cell lung cancer ( 23144319)	Wegener's granulomatosis ( 23740775)
Protein-Protein Interactions		15 interactors: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UMPS ZBTB16 ZHX1	1 interactors: DLST
Entrez ID		1743	79080
HPRD ID		00520	08322
Ensembl ID		ENSG00000119689	ENSG00000110104
Uniprot IDs		B7Z6J1 P36957	Q9H6F5
PDB IDs
Enriched GO Terms of Interacting Partners?			L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Lysine Catabolic Process Acetyl-CoA Metabolic Process Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Aerobic Respiration Acyl-CoA Metabolic Process Cellular Amino Acid Catabolic Process Cellular Respiration Carboxylic Acid Catabolic Process Alpha-amino Acid Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Cofactor Metabolic Process Sulfur Compound Metabolic Process Generation Of Precursor Metabolites And Energy Cellular Amino Acid Metabolic Process
Tagcloud ?		acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis
Tagcloud (Difference) ?		acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis
Tagcloud (Intersection) ?