DLST and RUSC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLST	RUSC2
Gene Name		dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	RUN and SH3 domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrial Matrix Membrane Oxoglutarate Dehydrogenase Complex Extracellular Vesicular Exosome	Cytosol Cytoplasmic Vesicle Extracellular Vesicular Exosome
	Molecular Function	Dihydrolipoyllysine-residue Succinyltransferase Activity	Protein Binding Rab GTPase Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle Lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process	Biological_process
Pathways		Lysine catabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Metabolism of amino acids and derivatives Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		Non-small cell lung cancer ( 23144319)
Protein-Protein Interactions		15 interactors: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UMPS ZBTB16 ZHX1	9 interactors: DLST EGFR GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SRPR
Entrez ID		1743	9853
HPRD ID		00520	18009
Ensembl ID		ENSG00000119689	ENSG00000198853
Uniprot IDs		B7Z6J1 P36957	Q8N2Y8
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Protein Metabolic Process Virion Assembly Mitotic Cell Cycle Rab Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Alkanesulfonate Metabolic Process ER To Golgi Vesicle-mediated Transport Positive Regulation Of Nucleocytoplasmic Transport Cell Cycle Cellular Protein Localization Positive Regulation Of Cellular Metabolic Process Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of RNA Export From Nucleus Astrocyte Activation Establishment Of Protein Localization L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Cytoplasmic Transport Interleukin-8 Production Activation Of Phospholipase A2 Activity Autophagy Positive Regulation Of Phospholipase A2 Activity Viral Life Cycle Response To Cobalamin Response To UV-A Regulation Of Nucleocytoplasmic Transport Response To Hydroxyisoflavone Protein Localization Membrane Organization Ras Protein Signal Transduction Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Establishment Of Protein Localization To Membrane Positive Regulation Of Intracellular Transport Intracellular Protein Transport Lysine Catabolic Process Cargo Loading Into Vesicle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Golgi Vesicle Transport Positive Regulation Of Catenin Import Into Nucleus Growth Hormone Secretion Positive Regulation Of Hydrolase Activity Regulation Of Phospholipase A2 Activity Regulation Of RNA Export From Nucleus Regulation Of Superoxide Anion Generation Positive Regulation Of Cellular Protein Metabolic Process See more
Tagcloud ?		acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis	akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?		acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis	akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?