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CEP57L1 and LZTS2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CEP57L1
LZTS2
Gene Name
centrosomal protein 57kDa-like 1
leucine zipper, putative tumor suppressor 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cellular_component
Cytoplasm
Microtubule Organizing Center
Microtubule
Cytoplasm
Centrosome
Microtubule
Midbody
Molecular Function
Molecular_function
Microtubule Binding
Identical Protein Binding
Gamma-tubulin Binding
Protein Binding
Biological Process
Biological_process
Microtubule Anchoring
Cytokinesis
Kidney Development
Mitotic Nuclear Division
Negative Regulation Of Cell Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
69 interactors:
ALOX5
AP1M1
ARNT2
BRCA1
BYSL
C6orf165
CALCOCO2
CARD9
CCDC102B
CCDC136
CCDC57
CDR2
CEP44
CEP55
CEP63
CEP70
DISC1
DYDC1
EXOC8
FAM161A
FAM9B
GADD45G
GOLGA1
GOLGA2
HAUS1
HDDC3
HGS
IKZF1
KATNAL1
KIFC3
KLC3
KLC4
KRT13
KRT19
KRT31
KRT38
KRT40
LENG1
LMO3
LZTS2
MAGEA1
MAGEA2B
MDFI
MEOX2
MFAP1
MID2
MORF4L1
MTUS2
MYO15B
NUP62
PKN1
PNMA5
PPL
RAD51D
RINT1
ROPN1
SNAP47
SNAPC3
SPERT
TAB3
TCEB3
TFIP11
TRAF2
TRAPPC2L
TRIM54
TRIP6
TSGA10
TXLNA
TXLNB
172 interactors:
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARHGAP32
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P5
BYSL
C14orf105
C19orf66
C1orf109
C20orf195
C6orf165
C8orf33
CARD9
CBX8
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CEP57L1
CHCHD3
CLIP4
CNNM3
COPB1
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DYRK1A
DYRK1B
DYRK2
EHHADH
EIF3D
EIF4E2
FAM103A1
FAM107A
FAM124B
FAM161A
FAM74A4
FANCL
FBF1
FEM1C
FGF12
FKBP6
FRG1
FRMD6
GCC1
GEM
GFI1B
GMCL1P1
GNL3L
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HSPD1
IQCE
KAT5
KAZN
KIAA1683
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
MAB21L3
MAGEB4
MEMO1
MORF4L1
MORF4L2
MORN3
MOS
MTA1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
OTUB2
PAK7
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R18
PQBP1
PRKAB2
PSMA1
QARS
RAC1
RAD51D
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3RF2
SLC15A3
SLC25A6
SLU7
SMIM3
SNHG11
SNW1
SNX31
SPATA2
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
TBC1D7
TCEA2
TCHP
TEAD4
THAP10
THAP7
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TTC23
TXNL4A
USF2
USP2
UTP14C
WDYHV1
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF20
ZNF250
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
Entrez ID
285753
84445
HPRD ID
10792
14341
Ensembl ID
ENSG00000183137
ENSG00000107816
Uniprot IDs
G5E992
Q8IYX8
Q9BRK4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of JNK Cascade
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of JNK Cascade
Organelle Organization
Microtubule-based Process
Regulation Of Stress-activated MAPK Cascade
Regulation Of MAPK Cascade
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Cell Cycle
Regulation Of Signal Transduction
Microtubule Severing
Regulation Of Signaling
I-kappaB Kinase/NF-kappaB Signaling
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of Intracellular Signal Transduction
Microtubule Cytoskeleton Organization
Regulation Of MAP Kinase Activity
Positive Regulation Of MAPK Cascade
Positive Regulation Of JUN Kinase Activity
Cellular Localization
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Spindle Assembly
Positive Regulation Of Protein Modification Process
Regulation Of JUN Kinase Activity
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
JNK Cascade
Negative Regulation Of Protein Acetylation
Centrosome Organization
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of MAP Kinase Activity
Mitotic Cell Cycle
Positive Regulation Of Transferase Activity
Microtubule Organizing Center Organization
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cell Cycle Process
Cell Differentiation Involved In Embryonic Placenta Development
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Neutrophil Differentiation
Positive Regulation Of Histone H4-K20 Methylation
Leukotriene Production Involved In Inflammatory Response
Positive Regulation Of Glucocorticoid Receptor Signaling Pathway
Spliceosomal Complex Disassembly
Positive Regulation Of Histone H4-K16 Acetylation
Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
RNA Metabolic Process
Gene Expression
Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of Gene Expression
Nitrogen Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Ribonucleoprotein Complex Biogenesis
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Viral Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription, DNA-templated
Regulation Of Cellular Process
Positive Regulation Of Cellular Metabolic Process
Organelle Organization
RNA Processing
Ribonucleoprotein Complex Assembly
Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecular Complex Assembly
Negative Regulation Of Gene Expression
Cellular Response To DNA Damage Stimulus
RNA Splicing
MRNA Processing
Regulation Of Protein Metabolic Process
Transcription From RNA Polymerase II Promoter
MRNA Splicing, Via Spliceosome
MRNA Metabolic Process
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Cell Cycle
Negative Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of T Cell Activation
Cellular Process
Positive Regulation Of Homotypic Cell-cell Adhesion
Regulation Of Cell Cycle
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Tagcloud
?
a549
anticancer
chemotherapeutic
clones
credits
effectively
exposing
gltscr2
lats1
making
mdr1
nf1
paclitaxel
panel
predetermined
profiling
pten
regards
screen
screened
shrna
shrnas
smad4
st14
suppressors
tumorigenesis
tumorigenic
vhl
wt1
Tagcloud (Difference)
?
a549
anticancer
chemotherapeutic
clones
credits
effectively
exposing
gltscr2
lats1
making
mdr1
nf1
paclitaxel
panel
predetermined
profiling
pten
regards
screen
screened
shrna
shrnas
smad4
st14
suppressors
tumorigenesis
tumorigenic
vhl
wt1
Tagcloud (Intersection)
?