CEP57L1 and LZTS2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP57L1	LZTS2
Gene Name		centrosomal protein 57kDa-like 1	leucine zipper, putative tumor suppressor 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Microtubule Organizing Center Microtubule	Cytoplasm Centrosome Microtubule Midbody
	Molecular Function	Molecular_function Microtubule Binding Identical Protein Binding Gamma-tubulin Binding	Protein Binding
	Biological Process	Biological_process Microtubule Anchoring	Cytokinesis Kidney Development Mitotic Nuclear Division Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Microtubule Severing Nuclear Export Spindle Midzone Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		69 interactors: ALOX5 AP1M1 ARNT2 BRCA1 BYSL C6orf165 CALCOCO2 CARD9 CCDC102B CCDC136 CCDC57 CDR2 CEP44 CEP55 CEP63 CEP70 DISC1 DYDC1 EXOC8 FAM161A FAM9B GADD45G GOLGA1 GOLGA2 HAUS1 HDDC3 HGS IKZF1 KATNAL1 KIFC3 KLC3 KLC4 KRT13 KRT19 KRT31 KRT38 KRT40 LENG1 LMO3 LZTS2 MAGEA1 MAGEA2B MDFI MEOX2 MFAP1 MID2 MORF4L1 MTUS2 MYO15B NUP62 PKN1 PNMA5 PPL RAD51D RINT1 ROPN1 SNAP47 SNAPC3 SPERT TAB3 TCEB3 TFIP11 TRAF2 TRAPPC2L TRIM54 TRIP6 TSGA10 TXLNA TXLNB	172 interactors: ABT1 AEN ANKRD11 ANKRD36BP1 AP1M1 ARHGAP32 ARMC7 ARNT2 ATPAF2 BAHD1 BEX2 BMS1P5 BYSL C14orf105 C19orf66 C1orf109 C20orf195 C6orf165 C8orf33 CARD9 CBX8 CCDC85B CCNC CCNG1 CCNK CDC23 CDK18 CDKL3 CEP57L1 CHCHD3 CLIP4 CNNM3 COPB1 CWF19L2 DCUN1D1 DGCR6 DGCR6L DYRK1A DYRK1B DYRK2 EHHADH EIF3D EIF4E2 FAM103A1 FAM107A FAM124B FAM161A FAM74A4 FANCL FBF1 FEM1C FGF12 FKBP6 FRG1 FRMD6 GCC1 GEM GFI1B GMCL1P1 GNL3L GPATCH2L GRB2 HLA-DPB1 HM13 HOMER2 HSPD1 IQCE KAT5 KAZN KIAA1683 KIF9 KIFC3 KPNA2 LASP1 LCK LIN37 LMO1 LMO2 MAB21L3 MAGEB4 MEMO1 MORF4L1 MORF4L2 MORN3 MOS MTA1 NCBP2 NCK2 NDE1 NEBL NEK6 NINL NIP7 OTUB2 PAK7 PITX1 PKP4 PLEKHN1 POLDIP3 POLR1C PPP1R18 PQBP1 PRKAB2 PSMA1 QARS RAC1 RAD51D RBFOX1 RBM15 RBM41 RBPMS RCOR3 RHNO1 RHOXF2 RIN1 RNF32 RNF41 RTP5 RUNX1T1 SCNM1 SH2D4A SH3RF2 SLC15A3 SLC25A6 SLU7 SMIM3 SNHG11 SNW1 SNX31 SPATA2 SPATA24 SPATC1L SPG7 SRSF2 STAC SUPV3L1 SUV39H1 TBC1D7 TCEA2 TCHP TEAD4 THAP10 THAP7 TNIP3 TRAF2 TRIM29 TRIM42 TSNAX TTC23 TXNL4A USF2 USP2 UTP14C WDYHV1 WT1-AS YTHDC1 ZBTB25 ZBTB38 ZGPAT ZKSCAN3 ZMAT1 ZMAT2 ZMYND19 ZNF20 ZNF250 ZNF417 ZNF426 ZNF446 ZNF490 ZNF512B ZNF572 ZNF581
Entrez ID		285753	84445
HPRD ID		10792	14341
Ensembl ID		ENSG00000183137	ENSG00000107816
Uniprot IDs		G5E992 Q8IYX8	Q9BRK4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Organelle Organization Microtubule-based Process Regulation Of Stress-activated MAPK Cascade Regulation Of MAPK Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Cell Cycle Regulation Of Signal Transduction Microtubule Severing Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Intracellular Signal Transduction Microtubule Cytoskeleton Organization Regulation Of MAP Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Cellular Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Spindle Assembly Positive Regulation Of Protein Modification Process Regulation Of JUN Kinase Activity Double-strand Break Repair Via Homologous Recombination Recombinational Repair JNK Cascade Negative Regulation Of Protein Acetylation Centrosome Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of MAP Kinase Activity Mitotic Cell Cycle Positive Regulation Of Transferase Activity Microtubule Organizing Center Organization Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cell Cycle Process Cell Differentiation Involved In Embryonic Placenta Development Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Spliceosomal Complex Disassembly Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint	RNA Metabolic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process Organelle Organization RNA Processing Ribonucleoprotein Complex Assembly Regulation Of Cellular Protein Metabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus RNA Splicing MRNA Processing Regulation Of Protein Metabolic Process Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Positive Regulation Of Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of T Cell Activation Cellular Process Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process
Tagcloud ?			a549 anticancer chemotherapeutic clones credits effectively exposing gltscr2 lats1 making mdr1 nf1 paclitaxel panel predetermined profiling pten regards screen screened shrna shrnas smad4 st14 suppressors tumorigenesis tumorigenic vhl wt1
Tagcloud (Difference) ?			a549 anticancer chemotherapeutic clones credits effectively exposing gltscr2 lats1 making mdr1 nf1 paclitaxel panel predetermined profiling pten regards screen screened shrna shrnas smad4 st14 suppressors tumorigenesis tumorigenic vhl wt1
Tagcloud (Intersection) ?