CEP57L1 and MFAP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP57L1	MFAP1
Gene Name		centrosomal protein 57kDa-like 1	microfibrillar-associated protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Microtubule Organizing Center Microtubule	Microfibril Extracellular Region
	Molecular Function	Molecular_function Microtubule Binding Identical Protein Binding Gamma-tubulin Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Biological_process Microtubule Anchoring	Biological_process Extracellular Matrix Organization
Pathways			Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		69 interactors: ALOX5 AP1M1 ARNT2 BRCA1 BYSL C6orf165 CALCOCO2 CARD9 CCDC102B CCDC136 CCDC57 CDR2 CEP44 CEP55 CEP63 CEP70 DISC1 DYDC1 EXOC8 FAM161A FAM9B GADD45G GOLGA1 GOLGA2 HAUS1 HDDC3 HGS IKZF1 KATNAL1 KIFC3 KLC3 KLC4 KRT13 KRT19 KRT31 KRT38 KRT40 LENG1 LMO3 LZTS2 MAGEA1 MAGEA2B MDFI MEOX2 MFAP1 MID2 MORF4L1 MTUS2 MYO15B NUP62 PKN1 PNMA5 PPL RAD51D RINT1 ROPN1 SNAP47 SNAPC3 SPERT TAB3 TCEB3 TFIP11 TRAF2 TRAPPC2L TRIM54 TRIP6 TSGA10 TXLNA TXLNB	47 interactors: AES AMOTL2 BEND7 CARD9 CCDC57 CDCA7L CEP55 CEP57L1 CEP70 COIL CSNK2A1 DHX38 DHX8 FAM9B FRA10AC1 FXR2 GKAP1 GOLGA2 HMBOX1 HSPB1 IK KATNBL1 KIFC3 KRT40 LDOC1 MAD1L1 MID2 MIPOL1 MTUS2 NDC80 PHC2 SART1 SMU1 SNIP1 SNW1 SSX2IP STX11 TADA2A TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB14 ZBTB8A ZFP64 ZNF398
Entrez ID		285753	4236
HPRD ID		10792	02569
Ensembl ID		ENSG00000183137	ENSG00000140259
Uniprot IDs		G5E992 Q8IYX8	P55081
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Organelle Organization Microtubule-based Process Regulation Of Stress-activated MAPK Cascade Regulation Of MAPK Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Cell Cycle Regulation Of Signal Transduction Microtubule Severing Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Intracellular Signal Transduction Microtubule Cytoskeleton Organization Regulation Of MAP Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Cellular Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Spindle Assembly Positive Regulation Of Protein Modification Process Regulation Of JUN Kinase Activity Double-strand Break Repair Via Homologous Recombination Recombinational Repair JNK Cascade Negative Regulation Of Protein Acetylation Centrosome Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of MAP Kinase Activity Mitotic Cell Cycle Positive Regulation Of Transferase Activity Microtubule Organizing Center Organization Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cell Cycle Process Cell Differentiation Involved In Embryonic Placenta Development Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Spliceosomal Complex Disassembly Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint	Mitotic Cell Cycle Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Mitotic Cell Cycle Process Transcription, DNA-templated RNA Biosynthetic Process Cell Cycle Process Cell Cycle RNA Splicing RNA Processing Regulation Of Chromosome Organization Regulation Of Tumor Necrosis Factor Biosynthetic Process MRNA Processing Negative Regulation Of Cellular Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Maturation Of 5S RRNA Regulation Of Metaphase Plate Congression Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Organelle Organization Regulation Of Mitotic Metaphase/anaphase Transition Microtubule Anchoring Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Gene Expression Positive Regulation Of Cytotoxic T Cell Differentiation Positive Regulation Of Vitamin D Receptor Signaling Pathway Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Binding Positive Regulation Of Tumor Necrosis Factor Production Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Cellular Macromolecule Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Zonula Adherens Maintenance Microtubule-based Process MRNA Export From Nucleus Regulation Of I-kappaB Kinase/NF-kappaB Signaling
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