CEP57L1 and EXOC8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP57L1	EXOC8
Gene Name		centrosomal protein 57kDa-like 1	exocyst complex component 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm Microtubule Organizing Center Microtubule	Exocyst Cytoplasm Late Endosome Cytosol Plasma Membrane Membrane Growth Cone
	Molecular Function	Molecular_function Microtubule Binding Identical Protein Binding Gamma-tubulin Binding	Protein Binding Ral GTPase Binding
	Biological Process	Biological_process Microtubule Anchoring	Exocyst Assembly Organelle Organization Endosome Organization Protein Transport Extracellular Matrix Disassembly Cellular Protein Metabolic Process Exocyst Localization Membrane Organization
Pathways			Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		69 interactors: ALOX5 AP1M1 ARNT2 BRCA1 BYSL C6orf165 CALCOCO2 CARD9 CCDC102B CCDC136 CCDC57 CDR2 CEP44 CEP55 CEP63 CEP70 DISC1 DYDC1 EXOC8 FAM161A FAM9B GADD45G GOLGA1 GOLGA2 HAUS1 HDDC3 HGS IKZF1 KATNAL1 KIFC3 KLC3 KLC4 KRT13 KRT19 KRT31 KRT38 KRT40 LENG1 LMO3 LZTS2 MAGEA1 MAGEA2B MDFI MEOX2 MFAP1 MID2 MORF4L1 MTUS2 MYO15B NUP62 PKN1 PNMA5 PPL RAD51D RINT1 ROPN1 SNAP47 SNAPC3 SPERT TAB3 TCEB3 TFIP11 TRAF2 TRAPPC2L TRIM54 TRIP6 TSGA10 TXLNA TXLNB	20 interactors: BLOC1S6 CCDC85B CEP57L1 EFHC2 EXOC2 HGS IKZF3 KRT15 KRT18 KRT19 KRT20 KRT31 LNX1 MBIP PCM1 RAB3IL1 RALA TADA2A ULK1 USHBP1
Entrez ID		285753	149371
HPRD ID		10792	09943
Ensembl ID		ENSG00000183137	ENSG00000116903
Uniprot IDs		G5E992 Q8IYX8	Q8IYI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of JNK Cascade Organelle Organization Microtubule-based Process Regulation Of Stress-activated MAPK Cascade Regulation Of MAPK Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Cell Cycle Regulation Of Signal Transduction Microtubule Severing Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Intracellular Signal Transduction Microtubule Cytoskeleton Organization Regulation Of MAP Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Cellular Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Spindle Assembly Positive Regulation Of Protein Modification Process Regulation Of JUN Kinase Activity Double-strand Break Repair Via Homologous Recombination Recombinational Repair JNK Cascade Negative Regulation Of Protein Acetylation Centrosome Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of MAP Kinase Activity Mitotic Cell Cycle Positive Regulation Of Transferase Activity Microtubule Organizing Center Organization Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cell Cycle Process Cell Differentiation Involved In Embryonic Placenta Development Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Spliceosomal Complex Disassembly Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint	Organelle Organization Protein Localization Post-Golgi Vesicle-mediated Transport Cytoskeleton Organization Golgi To Plasma Membrane Transport Membrane Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Microtubule Anchoring Histone H3 Acetylation Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Golgi Vesicle Transport Cellular Localization Cytoplasmic Transport Radial Glia Guided Migration Of Cerebellar Granule Cell Exocytosis Establishment Of Localization In Cell Membrane Raft Localization Protein Transport Histone Acetylation Vesicle-mediated Transport Establishment Of Protein Localization Internal Peptidyl-lysine Acetylation Regulation Of Tubulin Deacetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Intracellular Transport Maintenance Of Protein Location In Cell Intraciliary Transport Involved In Cilium Morphogenesis Secretion Of Lysosomal Enzymes Microtubule-based Transport Protein Acetylation Maintenance Of Protein Location Regulation Of Cell Differentiation Cytoskeleton-dependent Intracellular Transport Maintenance Of Location In Cell Organelle Assembly Negative Regulation Of Collateral Sprouting
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