LGALS9B and WWP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LGALS9B	WWP2
Gene Name		lectin, galactoside-binding, soluble, 9B	WW domain containing E3 ubiquitin protein ligase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Ubiquitin Ligase Complex Nucleus Cytoplasm Membrane Extracellular Vesicular Exosome
	Molecular Function	Carbohydrate Binding	RNA Polymerase II Transcription Factor Binding Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Ligase Activity
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Protein Modification Process Negative Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Transporter Activity Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell Negative Regulation Of Protein Transport Protein Autoubiquitination Protein K63-linked Ubiquitination Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways
Drugs
Diseases
GWAS			IgE levels ( 23146381)
Protein-Protein Interactions		3 interactors: DAB1 PRTFDC1 WWP2	53 interactors: ANKRD44 ARRDC1 ATN1 CDC34 CLCN5 CPSF6 DAG1 DIDO1 EGR2 EWSR1 FAM189A2 FBXL18 HNRNPUL1 IL2RG IL6R LGALS9B NDFIP2 PAIP1 PDLIM7 POLR2A POU5F1 RASA1 RNF11 RUSC1 SCAMP3 SCN5A SCNN1A SCNN1B SCNN1G SF1 SFTPC SMAD3 SMAD7 SNRPC SPG20 TFAP2A TNK2 TP53BP2 TRAF4 UBC UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2J2 UBE2K UBE2L3 USP7 VASP VPS37C WBP1 WBP2 WIPF1
Entrez ID		284194	11060
HPRD ID		18932	03812
Ensembl ID		ENSG00000170298	ENSG00000198373
Uniprot IDs		Q3B8N2	B4DHF6 O00308
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Cerebellum Structural Organization Lateral Motor Column Neuron Migration Spinal Cord Motor Neuron Migration Radial Glia Guided Migration Of Purkinje Cell Golgi Localization Negative Regulation Of Astrocyte Differentiation Midgut Development Anatomical Structure Arrangement Negative Regulation Of JAK-STAT Cascade Cell Migration In Hindbrain Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Astrocyte Differentiation Protein K63-linked Ubiquitination Locomotion Negative Regulation Of Glial Cell Differentiation Regulation Of Potassium Ion Transmembrane Transport Viral Entry Into Host Cell Negative Regulation Of Transporter Activity Protein Autoubiquitination Entry Into Host Cell Adult Walking Behavior Cerebellum Morphogenesis Hindbrain Morphogenesis Ventral Spinal Cord Development Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Potassium Ion Transport Cerebral Cortex Radially Oriented Cell Migration Negative Regulation Of Axonogenesis Regulation Of Glial Cell Differentiation Cerebral Cortex Cell Migration Regulation Of JAK-STAT Cascade Negative Regulation Of Cell Morphogenesis Involved In Differentiation Telencephalon Cell Migration Interaction With Host Forebrain Cell Migration Regulation Of Gliogenesis Spinal Cord Development Adult Locomotory Behavior Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cerebellum Development Negative Regulation Of Neuron Projection Development Metencephalon Development Digestive Tract Development Dendrite Development Negative Regulation Of Cell Projection Organization Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Digestive System Development Regulation Of Axonogenesis	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasomal Protein Catabolic Process Transcription Initiation From RNA Polymerase II Promoter Excretion Response To Organic Substance DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Ubiquitination Positive Regulation Of Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Sodium Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Gene Expression Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Transcription, DNA-templated Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Stimulus Positive Regulation Of Ossification Regulation Of Ossification RNA Biosynthetic Process Regulation Of Protein Ubiquitination Apoptotic Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Regulation Of Cellular Protein Metabolic Process Viral Process Apoptotic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Protein Catabolic Process RNA Processing Multicellular Organismal Water Homeostasis Programmed Cell Death Negative Regulation Of Transcription By Competitive Promoter Binding Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Proteolysis Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?			accelerating anticancer biomarker cascade catalyzes contributes counterparts deleted dramatic e3 encodes final homologue ligase ligases malignancies member nedd4 neoplastic oscc osccs pi3k promotion pten ten tensin tumoral ubiquitination
Tagcloud (Difference) ?			accelerating anticancer biomarker cascade catalyzes contributes counterparts deleted dramatic e3 encodes final homologue ligase ligases malignancies member nedd4 neoplastic oscc osccs pi3k promotion pten ten tensin tumoral ubiquitination
Tagcloud (Intersection) ?