FADS6 and INPP5K

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FADS6	INPP5K
Description		fatty acid desaturase 6	inositol polyphosphate-5-phosphatase K
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Ruffle Nucleus Cytoplasm Endoplasmic Reticulum Trans-Golgi Network Cytosol Plasma Membrane Membrane Ruffle Membrane Neuron Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Inositol-polyphosphate 5-phosphatase Activity Vasopressin Receptor Activity Protein Binding Inositol Bisphosphate Phosphatase Activity Hydrolase Activity Phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Phosphatidylinositol Trisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Lipid Phosphatase Activity Inositol Trisphosphate Phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process	In Utero Embryonic Development Regulation Of Glycogen Biosynthetic Process Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process G Protein-coupled Receptor Signaling Pathway Negative Regulation Of D-glucose Transmembrane Transport Actin Cytoskeleton Organization Response To Insulin Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Negative Regulation Of Dephosphorylation Positive Regulation Of Urine Volume Glucose Homeostasis Host-mediated Suppression Of Viral Transcription Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Glycerolipid Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Dephosphorylation Regulation Of Transport Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Calcium Ion Transport Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Negative Regulation Of Protein Targeting To Membrane Ruffle Assembly Cellular Response To Oxygen-containing Compound Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Renal Water Transport
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS			Mean platelet volume ( 27863252)
Interacting Genes		19 interacting genes: ARFIP2 CYSRT1 DIABLO FHL3 GAD2 INPP5K KRTAP10-7 KRTAP10-8 KRTAP3-3 KRTAP6-3 MDFI MTERF3 PBX3 PNKP RCHY1 TMEM14B TRIM32 TTPA UBASH3A	23 interacting genes: ANXA7 ARL6IP1 ATP5PF BDNF CDKN1A CPTP FADS6 FATE1 FBXO7 GOLT1B HMOX2 HSPB1 KRT31 NCOR2 PBX3 PFDN1 SFT2D2 SMN1 TANK TK1 TNFRSF10D TNKS TTR
Entrez ID		283985	51763
HPRD ID		13285	08489
Ensembl ID		ENSG00000172782	ENSG00000132376
Uniprot IDs		A0A087WYB9 Q8N9I5	B7Z4V9 Q9BT40
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament
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