FADS6 and MTERF3

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		FADS6	MTERF3
Name		fatty acid desaturase 6	mitochondrial transcription termination factor 3
Structure		No pdb structure
GO Annotations	Cellular Component	Membrane	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water	Transcription Cis-regulatory Region Binding Nucleic Acid Binding DNA Binding Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process	Regulation Of DNA-templated Transcription Ribosome Biogenesis Negative Regulation Of DNA-templated Transcription Mitochondrial Ribosome Assembly Regulation Of Mitochondrial Transcription
Pathways		None	PINK1-PRKN Mediated Mitophagy rRNA modification in the mitochondrion Mitochondrial mRNA modification
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		19 interacting genes: ARFIP2 CYSRT1 DIABLO FHL3 GAD2 INPP5K KRTAP10-7 KRTAP10-8 KRTAP3-3 KRTAP6-3 MDFI MTERF3 PBX3 PNKP RCHY1 TMEM14B TRIM32 TTPA UBASH3A	28 interacting genes: ADGRE2 AGTRAP APOC1 APP ARL6IP1 CACFD1 CMTM5 ERG28 FADS6 FUNDC1 GPR108 HIGD1C MAL2 MIR34B PBX3 RHBDD2 SCAMP1 SLC17A9 SLC2A5 SLC50A1 STX8 SYNGR1 SYP TMEM14C UPF2 YIF1A ZDHHC21 ZFPL1
Entrez ID		283985	51001
HPRD ID		13285	10823
Ensembl ID		ENSG00000172782	ENSG00000156469
Uniprot IDs		A0A087WYB9 Q8N9I5	E5RIK9 Q96E29
PDB IDs		Not available	3M66
GO Terms Enriched among Interactors		Intermediate Filament	Membrane Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Apparatus Regulation Of Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Endoplasmic Reticulum Very-low-density Lipoprotein Particle Vesicle-mediated Transport Golgi Membrane