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GLUL and HIPK3
Number of citations of the paper that reports this interaction (PMID
20936779
)
48
Data Source:
BioGRID
(two hybrid)
GLUL
HIPK3
Gene Name
glutamate-ammonia ligase
homeodomain interacting protein kinase 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Rough Endoplasmic Reticulum
Cytosol
Perikaryon
Protein Complex
Axon Terminus
Extracellular Vesicular Exosome
Glial Cell Projection
Nucleus
Cytoplasm
PML Body
Molecular Function
Magnesium Ion Binding
Glutamate Decarboxylase Activity
Glutamate-ammonia Ligase Activity
ATP Binding
Glutamate Binding
Manganese Ion Binding
Identical Protein Binding
Dynein Light Chain Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
ATP Binding
Biological Process
Neurotransmitter Uptake
Glutamate Catabolic Process
Glutamine Biosynthetic Process
Synaptic Transmission
Cell Proliferation
Cellular Amino Acid Biosynthetic Process
Cellular Response To Starvation
Response To Glucose
Positive Regulation Of Insulin Secretion
Cellular Nitrogen Compound Metabolic Process
Small Molecule Metabolic Process
Positive Regulation Of Epithelial Cell Proliferation
Protein Homooligomerization
Positive Regulation Of Synaptic Transmission, Glutamatergic
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Apoptotic Process
MRNA Transcription
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Negative Regulation Of Apoptotic Process
Negative Regulation Of JUN Kinase Activity
Pathways
Astrocytic Glutamate-Glutamine Uptake And Metabolism
Neurotransmitter uptake and Metabolism In Glial Cells
Amino acid synthesis and interconversion (transamination)
Metabolism of amino acids and derivatives
Transmission across Chemical Synapses
Drugs
L-Glutamine
L-Glutamic Acid
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
CASP8AP2
CYP39A1
DYNLL1
HIPK1
HIPK3
HTR2A
ND5
NFKB1
NUDT18
PIAS1
PIAS2
PIAS3
PLEKHF2
PPARD
RABEPK
RBBP6
SKIL
UBE2I
36 interactors:
AR
ARRB2
C1QA
CREB1
DAXX
FADD
FAS
FLNC
GLUL
GORASP1
GRB2
HEYL
HNRNPA1
HNRNPA2B1
HNRNPH1
LIMD1
LIMK2
LIMS2
MBD1
MTMR4
NR2F2
RGS3
SIAH1
SIAH2
SKIL
SNIP1
SRSF1
SRSF5
SUMO1
TGFB1I1
TOX4
TP73
TRA2B
UBE2I
ZNF107
ZYX
Entrez ID
2752
10114
HPRD ID
00701
05111
Ensembl ID
ENSG00000135821
ENSG00000110422
Uniprot IDs
A8YXX4
P15104
Q9H422
PDB IDs
2OJW
2QC8
Enriched GO Terms of Interacting Partners
?
Protein Sumoylation
Transcription, DNA-templated
RNA Biosynthetic Process
Cell Death
Death
Regulation Of Signal Transduction
Nucleobase-containing Compound Metabolic Process
Regulation Of Signaling
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Peptidyl-lysine Modification
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Protein Sumoylation
Apoptotic Process
Regulation Of Transcription, DNA-templated
Gene Expression
MRNA Transcription
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Programmed Cell Death
Protein Modification By Small Protein Conjugation
Regulation Of RNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Protein Sumoylation
Apoptotic Signaling Pathway
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Signal Transduction
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Cell Differentiation
Intracellular Receptor Signaling Pathway
Androgen Receptor Signaling Pathway
Regulation Of Apoptotic Process
Cellular Metabolic Process
Peptidyl-amino Acid Modification
Response To Mechanical Stimulus
Regulation Of Cell Death
Regulation Of Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
DGDP Catabolic Process
DADP Catabolic Process
Negative Regulation Of Interleukin-12 Biosynthetic Process
Regulation Of Signaling
Regulation Of Signal Transduction
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Gene Expression
Regulation Of Metabolic Process
Regulation Of Gene Expression
Regulation Of Cellular Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Component Assembly
Negative Regulation Of Gene Expression
Negative Regulation Of Signal Transduction
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Signaling
Negative Regulation Of Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Signal Transduction
Regulation Of Transcription, DNA-templated
Heterocycle Metabolic Process
Motor Neuron Apoptotic Process
Transcription, DNA-templated
Cellular Aromatic Compound Metabolic Process
Protein Oligomerization
RNA Biosynthetic Process
Response To Organic Substance
Cellular Response To Organic Substance
RNA Splicing
Regulation Of Extrinsic Apoptotic Signaling Pathway
Viral Process
Regulation Of RNA Splicing
Cellular Metabolic Process
RNA Processing
Cellular Response To Growth Factor Stimulus
Androgen Receptor Signaling Pathway
Response To Growth Factor
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Signaling
Necroptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Tagcloud
?
bell
bgh
bio
blots
bromo
cnp
deoxyuridine
dlgap2
dor
fibrillary
gfap
gh
glutamine
grin2a
gs
haemoglobin
hbb
igf1
igf1r
inactivity
ionotropic
modestly
phosphodiesterase
postsynaptic
robustly
sapap2
synapse
synthetase
tg
Tagcloud (Difference)
?
bell
bgh
bio
blots
bromo
cnp
deoxyuridine
dlgap2
dor
fibrillary
gfap
gh
glutamine
grin2a
gs
haemoglobin
hbb
igf1
igf1r
inactivity
ionotropic
modestly
phosphodiesterase
postsynaptic
robustly
sapap2
synapse
synthetase
tg
Tagcloud (Intersection)
?