GLUL and ND5

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		GLUL	ND5
Gene Name		glutamate-ammonia ligase	NADH dehydrogenase, subunit 5 (complex I)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Rough Endoplasmic Reticulum Cytosol Perikaryon Protein Complex Axon Terminus Extracellular Vesicular Exosome Glial Cell Projection
	Molecular Function	Magnesium Ion Binding Glutamate Decarboxylase Activity Glutamate-ammonia Ligase Activity ATP Binding Glutamate Binding Manganese Ion Binding Identical Protein Binding Dynein Light Chain Binding
	Biological Process	Neurotransmitter Uptake Glutamate Catabolic Process Glutamine Biosynthetic Process Synaptic Transmission Cell Proliferation Cellular Amino Acid Biosynthetic Process Cellular Response To Starvation Response To Glucose Positive Regulation Of Insulin Secretion Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Protein Homooligomerization Positive Regulation Of Synaptic Transmission, Glutamatergic
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Neurotransmitter uptake and Metabolism In Glial Cells Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives Transmission across Chemical Synapses	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs		L-Glutamine L-Glutamic Acid
Diseases
GWAS
Protein-Protein Interactions		18 interactors: CASP8AP2 CYP39A1 DYNLL1 HIPK1 HIPK3 HTR2A ND5 NFKB1 NUDT18 PIAS1 PIAS2 PIAS3 PLEKHF2 PPARD RABEPK RBBP6 SKIL UBE2I	2 interactors: GLUL LIG4
Entrez ID		2752	4540
HPRD ID		00701	02467
Ensembl ID		ENSG00000135821
Uniprot IDs		A8YXX4 P15104	P03915 Q7GXZ2
PDB IDs		2OJW 2QC8
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Transcription, DNA-templated RNA Biosynthetic Process Cell Death Death Regulation Of Signal Transduction Nucleobase-containing Compound Metabolic Process Regulation Of Signaling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Protein Sumoylation Apoptotic Process Regulation Of Transcription, DNA-templated Gene Expression MRNA Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Programmed Cell Death Protein Modification By Small Protein Conjugation Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Protein Sumoylation Apoptotic Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Signal Transduction Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Differentiation Intracellular Receptor Signaling Pathway Androgen Receptor Signaling Pathway Regulation Of Apoptotic Process Cellular Metabolic Process Peptidyl-amino Acid Modification Response To Mechanical Stimulus Regulation Of Cell Death Regulation Of Cell Differentiation Positive Regulation Of Fat Cell Differentiation DGDP Catabolic Process DADP Catabolic Process Negative Regulation Of Interleukin-12 Biosynthetic Process	DNA Ligation Involved In DNA Recombination Glutamine Biosynthetic Process Lagging Strand Elongation Pro-B Cell Differentiation Glutamate Catabolic Process Establishment Of Integrated Proviral Latency Establishment Of Viral Latency Immunoglobulin V(D)J Recombination DNA Ligation Involved In DNA Repair T Cell Receptor V(D)J Recombination Lymphoid Progenitor Cell Differentiation Cell Proliferation Neurotransmitter Uptake Dicarboxylic Acid Catabolic Process DNA Ligation Positive Regulation Of Cell Proliferation Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Synaptic Transmission, Glutamatergic Glutamate Metabolic Process Isotype Switching V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Response To Lithium Ion DNA Strand Elongation Response To X-ray Somatic Recombination Of Immunoglobulin Gene Segments Glutamine Metabolic Process Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response Regulation Of Cell Proliferation B Cell Activation Involved In Immune Response Cellular Response To Stress Response To Gamma Radiation Neuron Apoptotic Process Immunoglobulin Production Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Insulin Secretion Neuron Death T Cell Differentiation In Thymus Somatic Stem Cell Maintenance Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Nucleotide-excision Repair Dicarboxylic Acid Metabolic Process Regulation Of Fibroblast Proliferation Positive Regulation Of Hormone Secretion
Tagcloud ?		bell bgh bio blots bromo cnp deoxyuridine dlgap2 dor fibrillary gfap gh glutamine grin2a gs haemoglobin hbb igf1 igf1r inactivity ionotropic modestly phosphodiesterase postsynaptic robustly sapap2 synapse synthetase tg	accumulates bak bax bcl binds cytoplasm cytoplasmic demonstrates exhibit g13289a inducing invasion invasiveness liberating link notion p53 prevents promotes regulators reveals ros substitute supporting suppresses suppressing thereby w xl
Tagcloud (Difference) ?		bell bgh bio blots bromo cnp deoxyuridine dlgap2 dor fibrillary gfap gh glutamine grin2a gs haemoglobin hbb igf1 igf1r inactivity ionotropic modestly phosphodiesterase postsynaptic robustly sapap2 synapse synthetase tg	accumulates bak bax bcl binds cytoplasm cytoplasmic demonstrates exhibit g13289a inducing invasion invasiveness liberating link notion p53 prevents promotes regulators reveals ros substitute supporting suppresses suppressing thereby w xl
Tagcloud (Intersection) ?