GLUL and RABEPK

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GLUL	RABEPK
Gene Name		glutamate-ammonia ligase	Rab9 effector protein with kelch motifs
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Rough Endoplasmic Reticulum Cytosol Perikaryon Protein Complex Axon Terminus Extracellular Vesicular Exosome Glial Cell Projection	Endosome Plasma Membrane Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Magnesium Ion Binding Glutamate Decarboxylase Activity Glutamate-ammonia Ligase Activity ATP Binding Glutamate Binding Manganese Ion Binding Identical Protein Binding Dynein Light Chain Binding
	Biological Process	Neurotransmitter Uptake Glutamate Catabolic Process Glutamine Biosynthetic Process Synaptic Transmission Cell Proliferation Cellular Amino Acid Biosynthetic Process Cellular Response To Starvation Response To Glucose Positive Regulation Of Insulin Secretion Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Protein Homooligomerization Positive Regulation Of Synaptic Transmission, Glutamatergic	Receptor-mediated Endocytosis Vesicle Docking Involved In Exocytosis
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Neurotransmitter uptake and Metabolism In Glial Cells Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives Transmission across Chemical Synapses
Drugs		L-Glutamine L-Glutamic Acid
Diseases
GWAS
Protein-Protein Interactions		18 interactors: CASP8AP2 CYP39A1 DYNLL1 HIPK1 HIPK3 HTR2A ND5 NFKB1 NUDT18 PIAS1 PIAS2 PIAS3 PLEKHF2 PPARD RABEPK RBBP6 SKIL UBE2I	7 interactors: GLUL PIKFYVE POR PRKRA RAB9A TMEM98 ZYX
Entrez ID		2752	10244
HPRD ID		00701	09337
Ensembl ID		ENSG00000135821	ENSG00000136933
Uniprot IDs		A8YXX4 P15104	Q7Z6M1
PDB IDs		2OJW 2QC8
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Transcription, DNA-templated RNA Biosynthetic Process Cell Death Death Regulation Of Signal Transduction Nucleobase-containing Compound Metabolic Process Regulation Of Signaling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Protein Sumoylation Apoptotic Process Regulation Of Transcription, DNA-templated Gene Expression MRNA Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Programmed Cell Death Protein Modification By Small Protein Conjugation Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Protein Sumoylation Apoptotic Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Signal Transduction Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Differentiation Intracellular Receptor Signaling Pathway Androgen Receptor Signaling Pathway Regulation Of Apoptotic Process Cellular Metabolic Process Peptidyl-amino Acid Modification Response To Mechanical Stimulus Regulation Of Cell Death Regulation Of Cell Differentiation Positive Regulation Of Fat Cell Differentiation DGDP Catabolic Process DADP Catabolic Process Negative Regulation Of Interleukin-12 Biosynthetic Process	Retrograde Transport, Endosome To Golgi Cellular Organofluorine Metabolic Process Nitrate Catabolic Process Nitric Oxide Catabolic Process Cellular Response To Stimulus Glutamine Biosynthetic Process Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Nitrate Metabolic Process Lipid Modification Endosomal Transport Response To Organic Substance Glutamate Catabolic Process Positive Regulation Of Cholesterol Biosynthetic Process Response To Stimulus Positive Regulation Of Cholesterol Metabolic Process Positive Regulation Of Steroid Hormone Biosynthetic Process Outer Ear Morphogenesis Positive Regulation Of Hormone Biosynthetic Process Positive Regulation Of Secretion Production Of SiRNA Involved In RNA Interference Neurotransmitter Uptake Dicarboxylic Acid Catabolic Process Carnitine Metabolic Process Stress Fiber Assembly RNA Interference Cellular Response To Follicle-stimulating Hormone Stimulus Regulation Of Cell Proliferation Amino-acid Betaine Metabolic Process Response To Nutrient Levels Negative Regulation Of Lipase Activity Regulation Of Cholesterol Biosynthetic Process Response To Extracellular Stimulus Response To Follicle-stimulating Hormone Phosphatidylinositol-3-phosphate Biosynthetic Process Cellular Response To Gonadotropin Stimulus Positive Regulation Of Synaptic Transmission, Glutamatergic Glutamate Metabolic Process Flavonoid Metabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Hormone Biosynthetic Process Positive Regulation Of Steroid Metabolic Process Middle Ear Morphogenesis Nitric Oxide Metabolic Process Regulation Of Cholesterol Metabolic Process Reactive Nitrogen Species Metabolic Process Positive Regulation Of Chondrocyte Differentiation Response To External Stimulus Cellular Response To Organic Substance Myelin Assembly Regulation Of Hormone Metabolic Process
Tagcloud ?		bell bgh bio blots bromo cnp deoxyuridine dlgap2 dor fibrillary gfap gh glutamine grin2a gs haemoglobin hbb igf1 igf1r inactivity ionotropic modestly phosphodiesterase postsynaptic robustly sapap2 synapse synthetase tg
Tagcloud (Difference) ?		bell bgh bio blots bromo cnp deoxyuridine dlgap2 dor fibrillary gfap gh glutamine grin2a gs haemoglobin hbb igf1 igf1r inactivity ionotropic modestly phosphodiesterase postsynaptic robustly sapap2 synapse synthetase tg
Tagcloud (Intersection) ?