RND1 and ARFIP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RND1	ARFIP2
Description		Rho family GTPase 1	ARF interacting protein 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Actin Cytoskeleton Membrane	Ruffle Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cell Cortex Membrane Trans-Golgi Network Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding	Protein Binding GTP Binding Phospholipid Binding Protein Domain Specific Binding GTP-dependent Protein Binding Small GTPase Binding Identical Protein Binding Cadherin Binding Phosphatidylinositol-4-phosphate Binding Membrane Curvature Sensor Activity
	Biological Process	Actin Filament Organization Negative Regulation Of Cell Adhesion Signal Transduction Small GTPase-mediated Signal Transduction Neuron Remodeling Regulation Of Actin Cytoskeleton Organization	Mitophagy Intracellular Protein Transport Autophagy Small GTPase-mediated Signal Transduction Intracellular Protein Localization Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Localization To Phagophore Assembly Site
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse RND1 GTPase cycle	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Malaria ( 31844061)
Interacting Genes		21 interacting genes: ARFIP2 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 UBXN11 ZNF212	61 interacting genes: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARL1 BLOC1S2 C19orf25 CDKN2A CDR1 CEP63 CMTM5 CYTH3 DGAT2L6 DMAP1 DTNBP1 FADS6 FSD2 GOLGA2 GSG1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 KRT16 LNX1 LY6D MAL2 MIEF1 MIEF2 NDRG4 NFE2L2 NRDE2 NUP62 PBX3 PKNOX2 PLP2 PPIF RAC1 RAC2 RAC3 REEP5 REL RND1 SCAMP1 SCAMP5 SDCBP SH3GLB1 SMG9 SNX1 SOCS2 STAT3 SYP TMEM255B TRIM54 TTPA USHBP1
Entrez ID		27289	23647
HPRD ID		12357	07209
Ensembl ID		ENSG00000172602	ENSG00000132254
Uniprot IDs		Q92730	A0A087X1E4 B4DUZ3 B4DXH2 P53365
PDB IDs		2CLS 2REX 3Q3J	1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?		Semaphorin Receptor Complex Semaphorin Receptor Activity Semaphorin-plexin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Synapse Assembly	Regulation Of Vesicle-mediated Transport Regulation Of Cellular Component Organization Vesicle-mediated Transport Regulation Of Transport Regulation Of Endocytosis GTPase Activity Cellular Localization Protein Binding Protein Transport Regulation Of Receptor-mediated Endocytosis GTP Binding Positive Regulation Of Transport Positive Regulation Of Cellular Component Organization Establishment Of Protein Localization Organelle Organization Regulation Of Postsynapse Organization Cerebral Cortex GABAergic Interneuron Development Intracellular Transport Regulation Of Organelle Organization Regulation Of Cellular Localization Membrane Organization Positive Regulation Of Establishment Of Protein Localization Intracellular Protein Transport Cortical Cytoskeleton Organization Regulation Of Hydrogen Peroxide Metabolic Process NADPH Oxidase Complex Intracellular Protein Localization PTB Domain Binding Regulation Of Dendritic Spine Development Respiratory Burst Lamellipodium Golgi Vesicle Transport Establishment Of Localization In Cell Positive Regulation Of Secretion By Cell Regulation Of Synapse Organization Negative Regulation Of Endocytosis Regulation Of Establishment Of Protein Localization Regulation Of Cytoskeleton Organization Synaptic Vesicle Membrane Erythrocyte Enucleation Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Secretion Regulation Of Receptor Internalization Postsynapse Cytoskeleton Organization Negative Regulation Of Receptor-mediated Endocytosis Endocytosis Protein Kinase Binding Intracellular Signaling Cassette Positive Regulation Of Mitotic Cytokinetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?