RND1

Description		Rho family GTPase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Actin Cytoskeleton Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Cell Adhesion Signal Transduction Small GTPase-mediated Signal Transduction Neuron Remodeling Regulation Of Actin Cytoskeleton Organization
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse RND1 GTPase cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Novel Interacting Genes		2 novel interacting genes: KRT6A SHMT2
Interacting Genes		21 interacting genes: ARFIP2 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 UBXN11 ZNF212
Entrez ID		27289
HPRD ID		12357
Ensembl ID		ENSG00000172602
Uniprot IDs		Q92730
PDB IDs		2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?		Semaphorin Receptor Complex Semaphorin Receptor Activity Semaphorin-plexin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Synapse Assembly
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