RND1 and UBXN11

Number of citations of the paper that reports this interaction (PMID 11940653)
17

Data Source:
BioGRID (pull down, affinity chromatography technology, biochemical)
HPRD (in vitro, in vivo, two hybrid)

		RND1	UBXN11
Gene Name		Rho family GTPase 1	UBX domain protein 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Adherens Junction	Cytoplasm Cytoskeleton
	Molecular Function	GTPase Activity Receptor Binding Protein Binding GTP Binding	Ubiquitin Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Axon Guidance Metabolic Process Neuron Remodeling	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Axon guidance Semaphorin interactions SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		12 interactors: ARHGAP5 CREB3L2 FRS2 FRS3 GRB7 ID3 PDE6D PLXNA1 PLXNB1 PLXNB2 UBXN11 ZNF212	18 interactors: AES C6orf165 EIF4E EIF4E2 ENKD1 PRKAA1 PRKAB2 PSMA1 RHOBTB3 RND1 RND2 RND3 RNF213 SCNM1 SH2D4A TRAF2 USHBP1 ZFYVE9
Entrez ID		27289	91544
HPRD ID		12357	10245
Ensembl ID		ENSG00000172602	ENSG00000158062
Uniprot IDs		Q92730	Q5T124
PDB IDs		2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?		Semaphorin-plexin Signaling Pathway Regulation Of Cell Migration Regulation Of Cell Motility Organ Development Regulation Of Locomotion Neuroblast Proliferation Regulation Of Cellular Component Movement Regulation Of Rho GTPase Activity Regulation Of Rho Protein Signal Transduction Generation Of Neurons Positive Regulation Of Axonogenesis Response To Stimulus Stem Cell Proliferation Neurogenesis Tissue Development Signal Transduction Neural Precursor Cell Proliferation Epithelium Development Gland Development System Development Morphogenesis Of An Epithelium Signaling Optic Placode Formation Involved In Camera-type Eye Formation Cell Communication Regulation Of Ras GTPase Activity Cell Surface Receptor Signaling Pathway Regulation Of Metabolic Process Optic Placode Formation Gland Morphogenesis Regulation Of Axonogenesis Regulation Of Cell Shape Semaphorin-plexin Signaling Pathway Involved In Bone Trabecula Morphogenesis Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Cell Differentiation Nervous System Development Tissue Morphogenesis Multicellular Organismal Development Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Ras Protein Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Fibroblast Growth Factor Regulation Of Catalytic Activity Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Anatomical Structure Development Anatomical Structure Morphogenesis	Signal Transduction Signaling Cell Communication Cellular Response To Stimulus Insulin Receptor Signaling Pathway Protein Autoubiquitination Cellular Response To Insulin Stimulus Response To Stimulus Response To Organic Substance Small GTPase Mediated Signal Transduction Intracellular Signal Transduction Cellular Response To Organic Substance Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Response To Insulin Response To Cytokine Regulation Of Cellular Protein Metabolic Process Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Regulation Of Protein Metabolic Process Cell Surface Receptor Signaling Pathway Cellular Response To Reactive Oxygen Species Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Cell Cycle Cytokine-mediated Signaling Pathway Response To Camptothecin Positive Regulation Of Anoikis Negative Regulation Of Cell Cycle Response To Peptide Hormone Cellular Response To Organonitrogen Compound Protein Heterooligomerization Response To Peptide Fatty Acid Biosynthetic Process Metabolic Process Cell Cycle Process Regulation Of Lipid Biosynthetic Process Negative Regulation Of Sphingolipid Biosynthetic Process Regulation Of Cellular Process Cell Cycle Arrest Regulation Of Protein Binding Negative Regulation Of Signal Transduction Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Transferase Activity Regulation Of Ceramide Biosynthetic Process Protein Ubiquitination Protein Polyubiquitination Negative Regulation Of Signaling
Tagcloud ?		bioinformatics colonization conversely conversion cooperated deregulated derepression disrupted gap gtpase inactivates inactivation mechanistic mesenchymal neoplastic p120 plexin polarity rap1 rarely ras restrains rho signalling spontaneous suppresses turn unappreciated undifferentiated
Tagcloud (Difference) ?		bioinformatics colonization conversely conversion cooperated deregulated derepression disrupted gap gtpase inactivates inactivation mechanistic mesenchymal neoplastic p120 plexin polarity rap1 rarely ras restrains rho signalling spontaneous suppresses turn unappreciated undifferentiated
Tagcloud (Intersection) ?