RND1 and PLXNB2

Number of citations of the paper that reports this interaction (PMID 12730235)
30

Data Source:
HPRD (two hybrid)

		RND1	PLXNB2
Gene Name		Rho family GTPase 1	plexin B2
Image
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Adherens Junction	Intracellular Integral Component Of Plasma Membrane Cell Surface Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Receptor Binding Protein Binding GTP Binding	Protein Binding Semaphorin Receptor Activity
	Biological Process	Actin Filament Organization Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Axon Guidance Metabolic Process Neuron Remodeling	Neural Tube Closure Regulation Of Protein Phosphorylation Neuroblast Proliferation Brain Development Regulation Of Cell Shape Regulation Of Rho GTPase Activity Positive Regulation Of Axonogenesis Semaphorin-plexin Signaling Pathway Regulation Of Neuron Migration
Pathways		Axon guidance Semaphorin interactions SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		12 interactors: ARHGAP5 CREB3L2 FRS2 FRS3 GRB7 ID3 PDE6D PLXNA1 PLXNB1 PLXNB2 UBXN11 ZNF212	7 interactors: ARHGEF11 ARHGEF12 CENPU HMOX2 PFDN1 PTN RND1
Entrez ID		27289	23654
HPRD ID		12357	05050
Ensembl ID		ENSG00000172602	ENSG00000196576
Uniprot IDs		Q92730	O15031
PDB IDs		2CLS 2REX 3Q3J	4E71
Enriched GO Terms of Interacting Partners?		Semaphorin-plexin Signaling Pathway Regulation Of Cell Migration Regulation Of Cell Motility Organ Development Regulation Of Locomotion Neuroblast Proliferation Regulation Of Cellular Component Movement Regulation Of Rho GTPase Activity Regulation Of Rho Protein Signal Transduction Generation Of Neurons Positive Regulation Of Axonogenesis Response To Stimulus Stem Cell Proliferation Neurogenesis Tissue Development Signal Transduction Neural Precursor Cell Proliferation Epithelium Development Gland Development System Development Morphogenesis Of An Epithelium Signaling Optic Placode Formation Involved In Camera-type Eye Formation Cell Communication Regulation Of Ras GTPase Activity Cell Surface Receptor Signaling Pathway Regulation Of Metabolic Process Optic Placode Formation Gland Morphogenesis Regulation Of Axonogenesis Regulation Of Cell Shape Semaphorin-plexin Signaling Pathway Involved In Bone Trabecula Morphogenesis Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Cell Differentiation Nervous System Development Tissue Morphogenesis Multicellular Organismal Development Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Ras Protein Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Fibroblast Growth Factor Regulation Of Catalytic Activity Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Anatomical Structure Development Anatomical Structure Morphogenesis	Axon Guidance Termination Of G-protein Coupled Receptor Signaling Pathway Nervous System Development Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Axonogenesis Multicellular Organismal Development Axon Development Anatomical Structure Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Actin Cytoskeleton Organization Small GTPase Mediated Signal Transduction Neuron Projection Morphogenesis Actin Filament-based Process Heme Oxidation Developmental Process Cell Morphogenesis Involved In Differentiation Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neurotrophin TRK Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin Signaling Pathway Neuron Development Positive Regulation Of Rho GTPase Activity Heme Catabolic Process Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway System Development Neuron Remodeling Cell Morphogenesis Regulation Of Rho GTPase Activity Neuron Differentiation Cytoskeleton Organization Cell Projection Organization Regulation Of Rho Protein Signal Transduction Apoptotic Signaling Pathway Locomotion Cell Cycle Positive Regulation Of Ras GTPase Activity Movement Of Cell Or Subcellular Component Organelle Organization CENP-A Containing Nucleosome Assembly Generation Of Neurons Neuron Maturation Neurogenesis Regulation Of Ras GTPase Activity Histone Exchange DNA Replication-independent Nucleosome Assembly
Tagcloud ?		bioinformatics colonization conversely conversion cooperated deregulated derepression disrupted gap gtpase inactivates inactivation mechanistic mesenchymal neoplastic p120 plexin polarity rap1 rarely ras restrains rho signalling spontaneous suppresses turn unappreciated undifferentiated
Tagcloud (Difference) ?		bioinformatics colonization conversely conversion cooperated deregulated derepression disrupted gap gtpase inactivates inactivation mechanistic mesenchymal neoplastic p120 plexin polarity rap1 rarely ras restrains rho signalling spontaneous suppresses turn unappreciated undifferentiated
Tagcloud (Intersection) ?