ARHGEF16 and TFG

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ARHGEF16	TFG
Gene Name		Rho guanine nucleotide exchange factor (GEF) 16	TRK-fused gene
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rho GTPase Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding	Signal Transducer Activity Protein Binding Identical Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Activation Of Rac GTPase Activity Activation Of Cdc42 GTPase Activity Positive Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Cell Chemotaxis Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Apoptotic Signaling Pathway	Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Rho GTPase cycle Signaling by GPCR GPCR downstream signaling Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE Signaling by Rho GTPases NRAGE signals death through JNK G alpha (12/13) signalling events p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS		Response to statin therapy ( 20339536)
Protein-Protein Interactions		4 interactors: LNX1 MAPK1IP1L TFG YWHAQ	30 interactors: ANXA11 ARHGEF16 ARL15 BOLL C14orf1 CEP55 CRMP1 CSTF2 EWSR1 GBP2 GPRASP1 GRB2 HNRNPF KIAA1377 MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TRIM25 TSSK2 VPS37C
Entrez ID		27237	10342
HPRD ID		12478	03932
Ensembl ID		ENSG00000130762	ENSG00000114354
Uniprot IDs		B3KTS4 B4DJM7 Q5VV41	Q05BK6 Q92734
PDB IDs		1X6B
Enriched GO Terms of Interacting Partners?			Response To Cytokine Cytokine-mediated Signaling Pathway Cell Separation After Cytokinesis Response To Interferon-beta JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Interferon-gamma-mediated Signaling Pathway Cellular Response To Growth Hormone Stimulus Cellular Response To Cytokine Stimulus Regulation Of B Cell Differentiation Immune System Process Cellular Response To Interferon-gamma Defense Response Positive Regulation Of Immune Response Acute-phase Response Response To Growth Hormone Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Interferon-gamma Cellular Response To Organic Substance Mitotic Cytokinesis Negative Regulation Of Type I Interferon Production Platelet Activation JAK-STAT Cascade Positive Regulation Of T Cell Activation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Activation Neurotrophin Signaling Pathway Innate Immune Response Cell Surface Receptor Signaling Pathway Abortive Mitotic Cell Cycle G-protein Coupled Receptor Catabolic Process Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Regulation Of Immune Response Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Cytokinesis, Completion Of Separation Acute Inflammatory Response Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Viral Process Positive Regulation Of Immune System Process T Cell Costimulation Receptor Metabolic Process Cell Cycle Immune Response-activating Cell Surface Receptor Signaling Pathway Response To External Stimulus Regulation Of Body Fluid Levels
Tagcloud ?			architecture associate cargo carriers coat coated compartments concentrate copii cup en ergic exit export flexible interface interorganellar laden leave neighboring octameric polymers route slows submicron tight traverse trk uncoating
Tagcloud (Difference) ?			architecture associate cargo carriers coat coated compartments concentrate copii cup en ergic exit export flexible interface interorganellar laden leave neighboring octameric polymers route slows submicron tight traverse trk uncoating
Tagcloud (Intersection) ?