ARHGEF16 and MAPK1IP1L

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ARHGEF16	MAPK1IP1L
Gene Name		Rho guanine nucleotide exchange factor (GEF) 16	mitogen-activated protein kinase 1 interacting protein 1-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rho GTPase Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding
	Biological Process	Small GTPase Mediated Signal Transduction Activation Of Rac GTPase Activity Activation Of Cdc42 GTPase Activity Positive Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Cell Chemotaxis Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Apoptotic Signaling Pathway
Pathways		Rho GTPase cycle Signaling by GPCR GPCR downstream signaling Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE Signaling by Rho GTPases NRAGE signals death through JNK G alpha (12/13) signalling events p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS		Response to statin therapy ( 20339536)
Protein-Protein Interactions		4 interactors: LNX1 MAPK1IP1L TFG YWHAQ	15 interactors: ARHGEF16 C1orf94 CEP55 EWSR1 HGS HNRNPUL1 LENG8 PDCD6 RBFOX2 SS18L1 SUMO1 SUMO1P1 TFG UBE2I VPS37C
Entrez ID		27237	93487
HPRD ID		12478	12647
Ensembl ID		ENSG00000130762	ENSG00000168175
Uniprot IDs		B3KTS4 B4DJM7 Q5VV41	Q8NDC0
PDB IDs		1X6B
Enriched GO Terms of Interacting Partners?			Protein Sumoylation
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