Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
GDF9 and MPHOSPH6
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
GDF9
MPHOSPH6
Gene Name
growth differentiation factor 9
M-phase phosphoprotein 6
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Cytoplasm
Nuclear Exosome (RNase Complex)
Exosome (RNase Complex)
Nucleus
Nucleolus
Cytoplasm
Molecular Function
Cytokine Activity
Transforming Growth Factor Beta Receptor Binding
Growth Factor Activity
RNA Binding
Protein Binding
Biological Process
Oocyte Growth
Transforming Growth Factor Beta Receptor Signaling Pathway
Female Gamete Generation
Positive Regulation Of Cell Proliferation
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Cell Growth
BMP Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of MAPK Cascade
Cell Development
SMAD Protein Signal Transduction
Regulation Of Progesterone Secretion
Maturation Of 5.8S RRNA
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
45 interactors:
ACVR2A
ADPGK
ANXA7
APLP1
BMP15
BMPR1A
BMPR1B
BMPR2
BTBD2
CCDC53
CDKN1A
CDKN2C
CRELD1
DLEU1
DNM2
FOXG1
FXYD6
GADD45G
ILF3
KDM1A
KIF22
LSM3
MOB4
MPHOSPH6
MYCBP
NDUFB9
ORAI2
PABPC4
PAFAH1B3
PCDHA4
PCYT2
PMF1
PRKRA
PSMD11
RAB27A
RSRC1
S100A8
SAT1
SERPINB9
SMN1
SNRPG
STRN4
TDGF1
TK1
TRIB3
24 interactors:
AATF
APLP1
ARHGAP18
C14orf1
DNM2
DYNLRB1
EIF3G
EXOSC10
FTL
GDF9
KNSTRN
LRIF1
NUPR1
PARN
RBM48
RPS20
SKIV2L2
SMARCA4
SNX9
THOP1
TLE1
TP53
UNC119
ZHX1
Entrez ID
2661
10200
HPRD ID
03560
16111
Ensembl ID
ENSG00000164404
ENSG00000135698
Uniprot IDs
B4DXG3
O60383
Q99547
PDB IDs
Enriched GO Terms of Interacting Partners
?
BMP Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Bone Mineralization
Positive Regulation Of Biomineral Tissue Development
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of Protein Metabolic Process
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Chondrocyte Proliferation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Developmental Process
Regulation Of Bone Mineralization
Positive Regulation Of Osteoblast Differentiation
Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Anatomical Structure Development
Positive Regulation Of Protein Modification Process
Nucleobase-containing Compound Metabolic Process
System Development
Cellular Nitrogen Compound Metabolic Process
Regulation Of Apoptotic Process
Positive Regulation Of Ossification
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Protein Metabolic Process
Multicellular Organismal Development
Positive Regulation Of Signal Transduction
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Immune System Process
Regulation Of Cell Death
RNA Metabolic Process
RNA Processing
Phosphate-containing Compound Metabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Protein Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Osteoblast Differentiation
Gene Expression
Negative Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Negative Regulation Of Transferase Activity
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Gene Expression
Regulation Of Phosphorylation
Regulation Of Cell Growth
Organ Development
Gastrulation
Positive Regulation Of Metabolic Process
Gene Expression
RNA Metabolic Process
Regulation Of Female Gonad Development
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Metabolic Process
Maturation Of 5.8S RRNA
Positive Regulation Of Protein Oligomerization
Ribonucleoprotein Complex Biogenesis
Regulation Of Cell Growth
Endocytosis
Regulation Of Protein Oligomerization
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Mitotic Cell Cycle Process
Nuclear-transcribed MRNA Catabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Negative Regulation Of Cell Growth
MRNA Catabolic Process
Negative Regulation Of Fibroblast Proliferation
Nitrogen Compound Metabolic Process
Mitotic Cell Cycle
Positive Regulation Of Metabolic Process
Regulation Of Protein Metabolic Process
Cell Division
Regulation Of Gene Expression
RNA Catabolic Process
Ribosome Biogenesis
Regulation Of Metabolic Process
Mitotic Cytokinesis
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Clathrin-mediated Endocytosis
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Membrane Organization
Growth
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Protein Modification Process
Negative Regulation Of Growth
Nucleobase-containing Compound Metabolic Process
Regulation Of Cellular Component Organization
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
RNA Processing
Regulation Of Apoptotic Process
Negative Regulation Of Macromitophagy
Negative Regulation Of Membrane Tubulation
Lipid Tube Assembly
Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis
Negative Regulation Of Caveolin-mediated Endocytosis
Oocyte Growth
Tagcloud
?
3h
bmp
bmp15
bmpr2
decapentaplegic
differing
granulosa
incorporation
involves
jnk
jun
kb
mapk
morphogenetic
mothers
ovine
p3h
pathways
signalling
sma
smad
smad1
smad2
steroid
stimulate
synergistic
synergistically
thymidine
utilised
Tagcloud (Difference)
?
3h
bmp
bmp15
bmpr2
decapentaplegic
differing
granulosa
incorporation
involves
jnk
jun
kb
mapk
morphogenetic
mothers
ovine
p3h
pathways
signalling
sma
smad
smad1
smad2
steroid
stimulate
synergistic
synergistically
thymidine
utilised
Tagcloud (Intersection)
?