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GDF9 and CCDC53
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
GDF9
CCDC53
Gene Name
growth differentiation factor 9
coiled-coil domain containing 53
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Cytoplasm
Actin Cytoskeleton
Intracellular Membrane-bounded Organelle
WASH Complex
Molecular Function
Cytokine Activity
Transforming Growth Factor Beta Receptor Binding
Growth Factor Activity
Protein Binding
Biological Process
Oocyte Growth
Transforming Growth Factor Beta Receptor Signaling Pathway
Female Gamete Generation
Positive Regulation Of Cell Proliferation
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Cell Growth
BMP Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of MAPK Cascade
Cell Development
SMAD Protein Signal Transduction
Regulation Of Progesterone Secretion
Biological_process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
45 interactors:
ACVR2A
ADPGK
ANXA7
APLP1
BMP15
BMPR1A
BMPR1B
BMPR2
BTBD2
CCDC53
CDKN1A
CDKN2C
CRELD1
DLEU1
DNM2
FOXG1
FXYD6
GADD45G
ILF3
KDM1A
KIF22
LSM3
MOB4
MPHOSPH6
MYCBP
NDUFB9
ORAI2
PABPC4
PAFAH1B3
PCDHA4
PCYT2
PMF1
PRKRA
PSMD11
RAB27A
RSRC1
S100A8
SAT1
SERPINB9
SMN1
SNRPG
STRN4
TDGF1
TK1
TRIB3
28 interactors:
ABI2
BLOC1S6
CCHCR1
CEP55
CKAP4
DTNBP1
GDF9
GOLGA2
HAUS1
HSBP1
IFT20
KDM1A
KRT6A
LAMC1
LUC7L2
MCRS1
MOB1B
NDC80
NUP62
OPTN
PBXIP1
PCM1
PTN
SDCBP
SNAP25
SYCE1
TXLNA
TXLNB
Entrez ID
2661
51019
HPRD ID
03560
13031
Ensembl ID
ENSG00000164404
ENSG00000120860
Uniprot IDs
B4DXG3
O60383
F5GZ97
Q9Y3C0
PDB IDs
Enriched GO Terms of Interacting Partners
?
BMP Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Bone Mineralization
Positive Regulation Of Biomineral Tissue Development
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of Protein Metabolic Process
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Chondrocyte Proliferation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Developmental Process
Regulation Of Bone Mineralization
Positive Regulation Of Osteoblast Differentiation
Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Anatomical Structure Development
Positive Regulation Of Protein Modification Process
Nucleobase-containing Compound Metabolic Process
System Development
Cellular Nitrogen Compound Metabolic Process
Regulation Of Apoptotic Process
Positive Regulation Of Ossification
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Protein Metabolic Process
Multicellular Organismal Development
Positive Regulation Of Signal Transduction
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Immune System Process
Regulation Of Cell Death
RNA Metabolic Process
RNA Processing
Phosphate-containing Compound Metabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Protein Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Phosphorylation
Regulation Of Osteoblast Differentiation
Gene Expression
Negative Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Negative Regulation Of Transferase Activity
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Gene Expression
Regulation Of Phosphorylation
Regulation Of Cell Growth
Organ Development
Gastrulation
Positive Regulation Of Metabolic Process
Organelle Organization
Cell Differentiation
Establishment Of Localization In Cell
Organelle Localization
Mitotic Cell Cycle
Microtubule-based Transport
Cytoskeleton-dependent Intracellular Transport
Cellular Localization
Developmental Process
Synaptic Vesicle Docking
Cell Cycle
Mitotic Cell Cycle Process
Cell Development
Nervous System Development
Cell Cycle Process
Protein Localization
Post-Golgi Vesicle-mediated Transport
Microtubule-based Process
Intracellular Transport
Generation Of Neurons
Cell Projection Organization
Anterograde Synaptic Vesicle Transport
Synaptic Vesicle Transport
Membrane Organization
Neurogenesis
Melanosome Organization
Pigment Granule Organization
Microtubule-based Movement
Anterograde Axon Cargo Transport
Establishment Of Organelle Localization
Neuron Development
Cellular Process
Multicellular Organismal Development
Cellular Component Assembly
Intraciliary Transport
Establishment Of Protein Localization
Anatomical Structure Development
Movement Of Cell Or Subcellular Component
Protein Localization To Golgi Apparatus
Cytoskeleton Organization
Neuron Differentiation
Cell Division
Regulation Of Primitive Erythrocyte Differentiation
Opsin Transport
Establishment Of Vesicle Localization
Axon Cargo Transport
Vesicle Organization
Vesicle Localization
Neuron Projection Development
Positive Regulation Of Cell Proliferation
Tagcloud
?
3h
bmp
bmp15
bmpr2
decapentaplegic
differing
granulosa
incorporation
involves
jnk
jun
kb
mapk
morphogenetic
mothers
ovine
p3h
pathways
signalling
sma
smad
smad1
smad2
steroid
stimulate
synergistic
synergistically
thymidine
utilised
Tagcloud (Difference)
?
3h
bmp
bmp15
bmpr2
decapentaplegic
differing
granulosa
incorporation
involves
jnk
jun
kb
mapk
morphogenetic
mothers
ovine
p3h
pathways
signalling
sma
smad
smad1
smad2
steroid
stimulate
synergistic
synergistically
thymidine
utilised
Tagcloud (Intersection)
?