GDF9 and PABPC4

Number of citations of the paper that reports this interaction (PMID 15383276)
99

Data Source:
HPRD (two hybrid)

		GDF9	PABPC4
Gene Name		growth differentiation factor 9	poly(A) binding protein, cytoplasmic 4 (inducible form)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm	Nucleus Cytoplasm Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Growth Factor Activity	Nucleotide Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding Poly(C) RNA Binding Poly(A) RNA Binding
	Biological Process	Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway Regulation Of Apoptotic Process Regulation Of MAPK Cascade Cell Development SMAD Protein Signal Transduction Regulation Of Progesterone Secretion	RNA Processing RNA Catabolic Process Translation Blood Coagulation
Pathways
Drugs
Diseases
GWAS			C-reactive protein ( 21300955) HDL cholesterol ( 20686565)
Protein-Protein Interactions		45 interactors: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CCDC53 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3	14 interactors: EEF1A1 GDF9 HAP1 IL7R MED31 PHLDA1 RIF1 SETDB1 SMAD9 SREK1 SRPK2 UBC XRN1 YWHAQ
Entrez ID		2661	8761
HPRD ID		03560	04557
Ensembl ID		ENSG00000164404	ENSG00000090621
Uniprot IDs		B4DXG3 O60383	B1ANR0 Q13310
PDB IDs
Enriched GO Terms of Interacting Partners?		BMP Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Chondrocyte Proliferation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Developmental Process Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Anatomical Structure Development Positive Regulation Of Protein Modification Process Nucleobase-containing Compound Metabolic Process System Development Cellular Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Ossification Nitrogen Compound Metabolic Process Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Signal Transduction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Immune System Process Regulation Of Cell Death RNA Metabolic Process RNA Processing Phosphate-containing Compound Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Osteoblast Differentiation Gene Expression Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Transferase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Gene Expression Regulation Of Phosphorylation Regulation Of Cell Growth Organ Development Gastrulation Positive Regulation Of Metabolic Process	RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anatomical Structure Development Cellular Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Death Transcription, DNA-templated Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Transcription, DNA-templated Developmental Process Nitrogen Compound Metabolic Process Response To Transforming Growth Factor Beta Regulation Of Nucleic Acid-templated Transcription RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Macromolecule Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Death Multicellular Organismal Development Regulation Of Metabolic Process Macromolecule Biosynthetic Process Cellular Response To Organic Substance Positive Regulation Of Cell Cycle Nuclear Speck Organization Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly FasL Biosynthetic Process Organ Development Brain Development Regulation Of Epidermal Growth Factor Receptor Signaling Pathway System Development BMP Signaling Pathway Head Development Regulation Of ERBB Signaling Pathway Midbrain Development Interleukin-7-mediated Signaling Pathway Oocyte Growth Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cilium Assembly
Tagcloud ?		3h bmp bmp15 bmpr2 decapentaplegic differing granulosa incorporation involves jnk jun kb mapk morphogenetic mothers ovine p3h pathways signalling sma smad smad1 smad2 steroid stimulate synergistic synergistically thymidine utilised
Tagcloud (Difference) ?		3h bmp bmp15 bmpr2 decapentaplegic differing granulosa incorporation involves jnk jun kb mapk morphogenetic mothers ovine p3h pathways signalling sma smad smad1 smad2 steroid stimulate synergistic synergistically thymidine utilised
Tagcloud (Intersection) ?