Wiki-Pi
About
Search
People
Updates
Search
GDF9 and BTBD2
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
GDF9
BTBD2
Description
growth differentiation factor 9
BTB domain containing 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
P-body
Cytoplasm
Cytosol
Molecular Function
Cytokine Activity
Growth Factor Activity
Protein Binding
Biological Process
Oocyte Growth
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Female Gamete Generation
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Growth
Regulation Of Progesterone Secretion
Neurogenesis
Pathways
Drugs
Diseases
GWAS
Asthma (
31619474
)
Mitochondrial DNA copy number (white blood cells) (
30704525
)
Platelet count (
27863252
32888494
)
Platelet distribution width (
32888494
)
Plateletcrit (
32888494
)
Interacting Genes
45 interacting genes:
ACVR2A
ADPGK
ANXA7
APLP1
BMP15
BMPR1A
BMPR1B
BMPR2
BTBD2
CDKN1A
CDKN2C
CRELD1
CRIPTO
DLEU1
DNM2
FOXG1
FXYD6
GADD45G
ILF3
KDM1A
KIF22
LSM3
MOB4
MPHOSPH6
MYCBP
NDUFB9
ORAI2
PABPC4
PAFAH1B3
PCDHA4
PCYT2
PMF1
PRKRA
PSMD11
RAB27A
RSRC1
S100A8
SAT1
SERPINB9
SMN1
SNRPG
STRN4
TK1
TRIB3
WASHC3
37 interacting genes:
BRD7
CCDC90B
CCNC
CDK2
CINP
COPS6
CRMP1
CUL3
DPPA4
EEF1A1
ERG28
FXR1
GAPDH
GBP2
GDF9
IGSF21
KPNA2
MLH1
NGB
NTAQ1
OSGIN1
PSMD5
PTN
RBM48
RUNX1
SETDB1
SMAD1
SMAD2
TDP2
TGFBR1
TLE1
TOP1
TP53
TRIM5
UBR1
UNC119
ZNF512B
Entrez ID
2661
55643
HPRD ID
03560
12252
Ensembl ID
ENSG00000164404
ENSG00000133243
Uniprot IDs
B4DXG3
O60383
Q9BX70
PDB IDs
3NO8
Enriched GO Terms of Interacting Partners
?
BMP Receptor Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Cellular Response To BMP Stimulus
Positive Regulation Of Bone Mineralization
Positive Regulation Of Biomineral Tissue Development
Positive Regulation Of Ossification
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Activin Receptor Activity, Type II
BMP Binding
Positive Regulation Of Osteoblast Differentiation
Tricuspid Valve Morphogenesis
Activin Receptor Signaling Pathway
Regulation Of Bone Mineralization
BMP Signaling Pathway
Transforming Growth Factor Beta Receptor Activity, Type I
Negative Regulation Of Chondrocyte Proliferation
Regionalization
Endochondral Bone Morphogenesis
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Developmental Process
Positive Regulation Of SMAD Protein Signal Transduction
HFE-transferrin Receptor Complex
Mitral Valve Morphogenesis
RNA Splicing, Via Transesterification Reactions
Regulation Of Ossification
Pharyngeal Arch Artery Morphogenesis
Osteoblast Differentiation
Mesenchyme Development
Endocardial Cushion Development
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Positive Regulation Of Programmed Cell Death
Pattern Specification Process
Regulation Of Osteoblast Differentiation
Dorsal/ventral Pattern Formation
Cellular Response To Growth Factor Stimulus
Regulation Of SMAD Protein Signal Transduction
Cellular Developmental Process
Cell Differentiation
SMN-Sm Protein Complex
FAR/SIN/STRIPAK Complex
Anterior/posterior Pattern Specification
Kinase Activity
Precatalytic Spliceosome
Atrioventricular Valve Morphogenesis
Epithelial Cell Proliferation
Protein Binding
Male Germ Cell Nucleus
Transforming Growth Factor Beta Receptor Signaling Pathway
I-SMAD Binding
Homomeric SMAD Protein Complex
Positive Regulation Of Gene Expression
Disordered Domain Specific Binding
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Nucleoplasm
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
SMAD Protein Complex
Trophoblast Cell Migration
Peptidyl-serine Phosphorylation
Heteromeric SMAD Protein Complex
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription Regulator Complex
Gastrulation
Embryonic Cleavage
Positive Regulation Of Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleus
Regulation Of Macromolecule Metabolic Process
Regulation Of Protein Metabolic Process
DNA-templated Transcription
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Female Gamete Generation
Primary MiRNA Processing
Co-SMAD Binding
Mesenchyme Development
Negative Regulation Of Long-term Synaptic Potentiation
Negative Regulation Of Neuroblast Proliferation
Negative Regulation Of Cell Cycle G1/S Phase Transition
Positive Regulation Of Metabolic Process
Regulation Of Primary Metabolic Process
Positive Regulation Of Dendrite Development
Ubiquitin Protein Ligase Binding
Mitotic G1 DNA Damage Checkpoint Signaling
Negative Regulation Of Macromolecule Biosynthetic Process
Chromatin Binding
Mitotic G1/S Transition Checkpoint Signaling
Regulation Of MiRNA Transcription
Cell Fate Commitment
Negative Regulation Of RNA Metabolic Process
Positive Regulation Of Multicellular Organismal Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
DNA Metabolic Process
Positive Regulation Of Type I Interferon Production
Regulation Of MiRNA Metabolic Process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?