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NUPR1 and PTMA
Number of citations of the paper that reports this interaction (PubMedID
19650074
)
0
Data Source:
BioGRID
(two hybrid)
NUPR1
PTMA
Description
nuclear protein 1, transcriptional regulator
prothymosin alpha
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Protein-DNA Complex
Intercellular Bridge
Perinuclear Region Of Cytoplasm
Nucleus
Nucleoplasm
Cytosol
Molecular Function
DNA Binding
Chromatin Binding
Transcription Coactivator Activity
Protein Binding
Acetyltransferase Activator Activity
Protein Binding
Histone Binding
DNA-binding Transcription Factor Binding
Histone Chaperone Activity
Biological Process
Acute Inflammatory Response
Negative Regulation Of Cell Population Proliferation
Male Gonad Development
Response To Toxic Substance
Regulation Of Autophagy
Negative Regulation Of Autophagy
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Skeletal Muscle Cell Differentiation
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of Apoptotic Process
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Neuron Apoptotic Process
Fibroblast Apoptotic Process
Negative Regulation Of Cell Cycle
Positive Regulation Of Cell Cycle
Negative Regulation Of Glycolytic Process
Positive Regulation Of DNA-templated Transcription
Fibroblast Proliferation
Negative Regulation Of Fibroblast Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Programmed Necrotic Cell Death
Protein-containing Complex Assembly
Positive Regulation Of Neuroinflammatory Response
Positive Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Autophagosome Assembly
Positive Regulation Of Oxidative Phosphorylation
Negative Regulation Of Epithelial Cell Apoptotic Process
Negative Regulation Of Type B Pancreatic Cell Proliferation
Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Female Gonad Development
Positive Regulation Of Fibroblast Apoptotic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Chromatin Organization
DNA-templated Transcription
Negative Regulation Of Apoptotic Process
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS
Alcohol consumption (drinks per week) (
30679032
)
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Body mass index (
28892062
)
Brain morphology (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Educational attainment (
25201988
)
Extremely high intelligence (
29520040
)
Household income (MTAG) (
31844048
)
Inflammatory bowel disease (
28067908
23128233
)
Inflammatory bowel disease (early onset) (
19915574
)
Intelligence (MTAG) (
29326435
)
Lamb consumption (
32066663
)
Offspring birth weight (
31043758
)
Refractive error (
32231278
)
Urinary metabolite levels in chronic kidney disease (
31959995
)
Eating disorders (purging via substances) (
23568457
)
Height (
18391951
)
Lymphocyte count (
27863252
32888494
)
Monocyte percentage of white cells (
32888494
)
Neutrophil count (
32888494
)
White blood cell count (
27863252
32888494
)
Interacting Genes
16 interacting genes:
ABCG8
ALDH1A1
EP300
KNSTRN
MAPRE1
MPHOSPH6
MSL1
NPY5R
PAXIP1
PTMA
RANBP1
RPL41
SEC11A
SET
STX18
SYNCRIP
43 interacting genes:
CASP3
CASP7
CCNA2
CCNB1
CDK1
CDK2
CDK4
CREBBP
EP300
ESR1
FNDC3B
GSK3A
H1-1
H2AC14
H2BC21
H2BC8
H3-4
H3C14
H4C1
H4C14
HDAC1
HDAC2
HSPA1A
IL7R
KEAP1
KPNA2
KPNB1
NCOR1
NUP62
NUPR1
NUTF2
PCNA
PHB2
RAN
RCC1
SET
SIN3A
STAT3
TERF1
TERF2
TERF2IP
VIPR1
ZDHHC17
Entrez ID
26471
5757
HPRD ID
17814
01778
Ensembl ID
ENSG00000176046
ENSG00000187514
Uniprot IDs
O60356
P06454
Q53S24
PDB IDs
2L9I
2MNQ
Enriched GO Terms of Interacting Partners
?
Nucleoplasm
Chromatin Organization
Chromatin Remodeling
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleus
Chromosome, Telomeric Region
Regulation Of Nucleobase-containing Compound Metabolic Process
Chromatin Binding
Protein Localization To Organelle
Chromosome Organization
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Nucleosome Assembly
Protein-containing Complex
Regulation Of Primary Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Protein Import Into Nucleus
Rhythmic Process
Negative Regulation Of Biosynthetic Process
Chromosome
Import Into Nucleus
Telomere Organization
Protein-DNA Complex Assembly
Nucleosome Organization
Regulation Of Macromolecule Biosynthetic Process
Structural Constituent Of Chromatin
Nuclear Telomere Cap Complex
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Macromolecule Metabolic Process
Protein Localization To Chromosome
Protein Localization To Nucleus
Positive Regulation Of Macromolecule Metabolic Process
Nucleosome
Positive Regulation Of Metabolic Process
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of RNA Metabolic Process
Regulation Of DNA Metabolic Process
Regulation Of Gene Expression
Chromatin
Regulation Of Generation Of Precursor Metabolites And Energy
Regulation Of Cell Population Proliferation
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Programmed Cell Death
DNA Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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