NUPR1 and RPL41

Number of citations of the paper that reports this interaction (PMID 19650074)
6

Data Source:
BioGRID (two hybrid)

		NUPR1	RPL41
Gene Name		nuclear protein, transcriptional regulator, 1	ribosomal protein L41
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Cytosolic Large Ribosomal Subunit
	Molecular Function	Molecular_function DNA Binding Chromatin Binding	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Acute Inflammatory Response Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Complex Assembly Protein Acetylation Male Gonad Development Response To Toxic Substance Cell Growth Positive Regulation Of Protein Modification Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Cycle Negative Regulation Of Fibroblast Proliferation Regulation Of Female Gonad Development	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Inflammatory bowel disease (early onset) ( 19915574)	Systemic sclerosis ( 21779181)
Protein-Protein Interactions		21 interactors: ABCG8 ALDH1A1 EP300 FUS KNSTRN MAPRE1 MPHOSPH6 MSL1 NACA NONO NPY5R PAXIP1 PSMD4 PTMA RAN RANBP1 RPL41 SEC11A SET STX18 SYNCRIP	7 interactors: APP CSNK2B IKBKG MAPK14 NUPR1 PRNP SRPK2
Entrez ID		26471	6171
HPRD ID		17814	17999
Ensembl ID		ENSG00000176046	ENSG00000229117
Uniprot IDs		O60356	P62945
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Viral Process Gene Expression Positive Regulation Of Protein Binding Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Organelle Organization Cell Cycle Signal Transduction By P53 Class Mediator Nitrogen Compound Metabolic Process Positive Regulation Of Binding Spindle Organization Cell Cycle Process Mitotic Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Protein Binding Regulation Of Microtubule-based Process Nucleobase-containing Compound Metabolic Process Organelle Organization Regulation Of Histone Acetylation RNA Metabolic Process Histone H4 Acetylation Protein Localization To Organelle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Apoptotic Process Histone H2B Acetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Histone H3-K36 Methylation Generation Of Ovulation Cycle Rhythm Negative Regulation Of Programmed Cell Death MRNA Metabolic Process Negative Regulation Of Cell Death Peptidyl-lysine Modification Regulation Of Binding Mitotic Cell Cycle Phase Transition Intracellular Transport Cell Cycle Phase Transition Chromosome Organization Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Cholesterol Absorption Cellular Process Rhythmic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Mitotic Nuclear Division Ribosomal Small Subunit Export From Nucleus Positive Regulation Of ER To Golgi Vesicle-mediated Transport N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Microtubule Plus-end Binding Endoplasmic Reticulum Membrane Organization Positive Regulation Of Skeletal Muscle Tissue Growth	Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Defense Response Cellular Copper Ion Homeostasis Chemotaxis Copper Ion Homeostasis Regulation Of Phosphorus Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Innate Immune Response Response To External Stimulus Phosphorylation Cell Differentiation Positive Regulation Of Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Cellular Component Assembly Positive Regulation Of Protein Modification Process Regulation Of Cell Cycle Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Apoptotic Process Toll-like Receptor 5 Signaling Pathway Programmed Cell Death Toll-like Receptor 10 Signaling Pathway Cell Death Death Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Cell Morphogenesis Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Cellular Response To Stimulus TRIF-dependent Toll-like Receptor Signaling Pathway Axon Guidance MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway System Development MyD88-dependent Toll-like Receptor Signaling Pathway Anatomical Structure Morphogenesis Toll-like Receptor 4 Signaling Pathway Locomotion Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Immune Response Growth Protein Phosphorylation
Tagcloud ?		95d altered arrest atpase c3orf1 carcinoma ccng2 col3a1 concurrently depleted depletion ecm focal inner introducing justified lung microarray migration mitochondrial notably preliminary pten remarkably timmdc1 timp3 translocase upregulated viable	11th anxa2 balb blastn differentially enriched euthanized infected inoculated inoculation messenger myeloma nktr parasite perform putative ranged rbbp4 sequenced sizes sp2 spiralis ssh subcutaneously subtractive trichinella twenty utilized weights
Tagcloud (Difference) ?		95d altered arrest atpase c3orf1 carcinoma ccng2 col3a1 concurrently depleted depletion ecm focal inner introducing justified lung microarray migration mitochondrial notably preliminary pten remarkably timmdc1 timp3 translocase upregulated viable	11th anxa2 balb blastn differentially enriched euthanized infected inoculated inoculation messenger myeloma nktr parasite perform putative ranged rbbp4 sequenced sizes sp2 spiralis ssh subcutaneously subtractive trichinella twenty utilized weights
Tagcloud (Intersection) ?