NUPR1 and MAPRE1

Number of citations of the paper that reports this interaction (PMID 19650074)
6

Data Source:
BioGRID (two hybrid)

		NUPR1	MAPRE1
Gene Name		nuclear protein, transcriptional regulator, 1	microtubule-associated protein, RP/EB family, member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Microtubule Cytoplasmic Microtubule Cortical Microtubule Cytoskeleton Cell Projection Membrane Microtubule Plus-end
	Molecular Function	Molecular_function DNA Binding Chromatin Binding	Protein Binding Protein C-terminus Binding Poly(A) RNA Binding Microtubule Plus-end Binding
	Biological Process	Acute Inflammatory Response Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Complex Assembly Protein Acetylation Male Gonad Development Response To Toxic Substance Cell Growth Positive Regulation Of Protein Modification Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Cycle Negative Regulation Of Fibroblast Proliferation Regulation Of Female Gonad Development	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Cell Proliferation Negative Regulation Of Microtubule Polymerization Protein Localization To Microtubule Cell Division Positive Regulation Of Microtubule Plus-end Binding
Pathways			Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Inflammatory bowel disease (early onset) ( 19915574)
Protein-Protein Interactions		21 interactors: ABCG8 ALDH1A1 EP300 FUS KNSTRN MAPRE1 MPHOSPH6 MSL1 NACA NONO NPY5R PAXIP1 PSMD4 PTMA RAN RANBP1 RPL41 SEC11A SET STX18 SYNCRIP	40 interactors: ABCB1 APC APC2 APP AURKB BCL3 CDK5RAP2 CLASP1 CLASP2 CLIP1 COPS5 COPS8 CSN3 CYLD DCTN1 HSPA1A IKBKG KAT2B KAT5 KIF2C LMO2 LRP1 MACF1 MAPRE2 MAPRE3 NAV1 NUPR1 PDE4DIP PIK3R4 POLE2 PQBP1 PSMA1 SPDYE2 STK11 TERF1 TRAF2 TRIO TROAP TUBA1A TUBB
Entrez ID		26471	22919
HPRD ID		17814	04379
Ensembl ID		ENSG00000176046	ENSG00000101367
Uniprot IDs		O60356	B4DM33 Q15691
PDB IDs			1PA7 1TXQ 1UEG 1VKA 1WU9 1YIB 1YIG 2HKQ 2HL3 2HL5 2QJZ 2R8U 3GJO 3TQ7
Enriched GO Terms of Interacting Partners?		Viral Process Gene Expression Positive Regulation Of Protein Binding Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Organelle Organization Cell Cycle Signal Transduction By P53 Class Mediator Nitrogen Compound Metabolic Process Positive Regulation Of Binding Spindle Organization Cell Cycle Process Mitotic Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Protein Binding Regulation Of Microtubule-based Process Nucleobase-containing Compound Metabolic Process Organelle Organization Regulation Of Histone Acetylation RNA Metabolic Process Histone H4 Acetylation Protein Localization To Organelle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Apoptotic Process Histone H2B Acetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Histone H3-K36 Methylation Generation Of Ovulation Cycle Rhythm Negative Regulation Of Programmed Cell Death MRNA Metabolic Process Negative Regulation Of Cell Death Peptidyl-lysine Modification Regulation Of Binding Mitotic Cell Cycle Phase Transition Intracellular Transport Cell Cycle Phase Transition Chromosome Organization Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Cholesterol Absorption Cellular Process Rhythmic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Mitotic Nuclear Division Ribosomal Small Subunit Export From Nucleus Positive Regulation Of ER To Golgi Vesicle-mediated Transport N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Microtubule Plus-end Binding Endoplasmic Reticulum Membrane Organization Positive Regulation Of Skeletal Muscle Tissue Growth	Cell Cycle Process Mitotic Cell Cycle Process Cell Cycle Mitotic Cell Cycle Mitotic Nuclear Division Regulation Of Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Cycle G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Microtubule-based Process Response To Stimulus Organelle Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Complex Assembly Regulation Of Cytoskeleton Organization Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Microtubule Depolymerization Regulation Of Chromosome Segregation Cullin Deneddylation Cellular Localization Regulation Of Wnt Signaling Pathway Establishment Or Maintenance Of Cell Polarity Response To Radiation Protein Deneddylation Negative Regulation Of Microtubule Polymerization Or Depolymerization Cellular Component Assembly Spindle Checkpoint Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Microtubule Bundle Formation Response To Light Stimulus Cellular Protein Complex Assembly Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Positive Regulation Of Transferase Activity
Tagcloud ?		95d altered arrest atpase c3orf1 carcinoma ccng2 col3a1 concurrently depleted depletion ecm focal inner introducing justified lung microarray migration mitochondrial notably preliminary pten remarkably timmdc1 timp3 translocase upregulated viable	akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Difference) ?		95d altered arrest atpase c3orf1 carcinoma ccng2 col3a1 concurrently depleted depletion ecm focal inner introducing justified lung microarray migration mitochondrial notably preliminary pten remarkably timmdc1 timp3 translocase upregulated viable	akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Intersection) ?