NUPR1 and RANBP1

Number of citations of the paper that reports this interaction (PubMedID 19650074)
0

Data Source:
BioGRID (two hybrid)

		NUPR1	RANBP1
Description		nuclear protein 1, transcriptional regulator	RAN binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Protein-DNA Complex Intercellular Bridge Perinuclear Region Of Cytoplasm	Nucleus Nuclear Envelope Nuclear Pore Cytoplasm Centrosome Cytosol
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Acetyltransferase Activator Activity	GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Small GTPase Binding Cadherin Binding
	Biological Process	Acute Inflammatory Response Negative Regulation Of Cell Population Proliferation Male Gonad Development Response To Toxic Substance Regulation Of Autophagy Negative Regulation Of Autophagy Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Neuron Apoptotic Process Fibroblast Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Negative Regulation Of Glycolytic Process Positive Regulation Of DNA-templated Transcription Fibroblast Proliferation Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Programmed Necrotic Cell Death Protein-containing Complex Assembly Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Autophagosome Assembly Positive Regulation Of Oxidative Phosphorylation Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Female Gonad Development Positive Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Nucleocytoplasmic Transport Signal Transduction Positive Regulation Of Mitotic Centrosome Separation
Pathways			Rev-mediated nuclear export of HIV RNA
Drugs			Copper Phenethyl Isothiocyanate
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30679032) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574) Intelligence (MTAG) ( 29326435) Lamb consumption ( 32066663) Offspring birth weight ( 31043758) Refractive error ( 32231278) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		16 interacting genes: ABCG8 ALDH1A1 EP300 KNSTRN MAPRE1 MPHOSPH6 MSL1 NPY5R PAXIP1 PTMA RANBP1 RPL41 SEC11A SET STX18 SYNCRIP	7 interacting genes: CD93 CEBPA MDM2 NUPR1 RAN RANGRF RCC1
Entrez ID		26471	5902
HPRD ID		17814	03110
Ensembl ID		ENSG00000176046	ENSG00000099901
Uniprot IDs		O60356	A0A140VK94 B3KUP2 B4DE76 F6WQW2 P43487
PDB IDs			1K5D 1K5G
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis Mitotic Spindle Organization Chromatin Binding Spindle Organization Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Response To Steroid Hormone Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Domain Specific Binding Nucleoplasm Protein-containing Complex Acute Inflammatory Response Positive Regulation Of Nucleocytoplasmic Transport RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Protein Heterodimerization Activity Response To Formaldehyde Cellular Response To Vitamin B1 Regulation Of Protein Catabolic Process Response To Vitamin Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Response To Vitamin B2 Regulation Of Cell Cycle C/EBP Complex Microtubule Cytoskeleton Organization Spindle Assembly Positive Regulation Of Intracellular Protein Transport Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Localization Signal Transduction By P53 Class Mediator Response To Toxic Substance Proline Dehydrogenase Activity RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Bundle Of His Cell Action Potential Regulation Of Heart Rate Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process CHOP-C/EBP Complex Response To Vitamin B1 Regulation Of Cellular Localization Response To Water-immersion Restraint Stress Regulation Of Nucleocytoplasmic Transport Cellular Response To Actinomycin D L-proline Catabolic Process To L-glutamate Negative Regulation Of Type B Pancreatic Cell Proliferation
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