CKB and SERP2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CKB	SERP2
Description		creatine kinase B	stress associated endoplasmic reticulum protein family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Nucleotide Binding Catalytic Activity Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Ubiquitin Protein Ligase Binding	Protein Binding
	Biological Process	Substantia Nigra Development Phosphocreatine Biosynthetic Process Futile Creatine Cycle	Response To Unfolded Protein Endoplasmic Reticulum Unfolded Protein Response
Pathways		Creatine metabolism RND3 GTPase cycle
Drugs		Creatine Phosphocreatine
Diseases
GWAS		Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Extremely high intelligence ( 29520040) Height ( 28552196 31562340) Schizophrenia ( 25056061)	Chronic obstructive pulmonary disease ( 30804561) Dupuytren's disease ( 28886342) Fasting insulin (dietary factor interaction) ( 24204828) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)
Interacting Genes		19 interacting genes: ACD ARIH2 ASB9 CKM CUL5 ERBB2 GOLGA2 ILK MLH1 OGT POT1 PPP1CA SERP2 SNCA TAB1 TERF1 TINF2 TRIM63 UBE3A	54 interacting genes: ALG10 AQP6 BIK BSCL2 CERS4 CISD2 CKB CYB561 CYBRD1 EBP ELOVL4 ERGIC3 EWSR1 FAM210B FCGR2A FFAR2 FNDC9 FRMD3 GET1 GKN1 GPR152 GPR42 HSD17B13 KASH5 LHFPL5 LMNA LYVE1 MTIF3 MUC1 NEMP1 OPRM1 PTGES RETREG3 RNASEK SCN3B SLC10A6 SLC30A4 SLC38A1 SLC38A7 SLC71A2 SPACA1 STOM STX1A TIMMDC1 TM4SF18 TM4SF19 TMED8 TMEM106C TMEM14B TMEM179B TMEM237 TMEM31 TMEM80 TMX2
Entrez ID		1152	387923
HPRD ID		00423	16590
Ensembl ID		ENSG00000166165	ENSG00000151778
Uniprot IDs		A0A0S2Z471 P12277 V9HWH2	Q8N6R1
PDB IDs		3B6R 3DRB 3DRE 6V9H 7BF1 7TUN
Enriched GO Terms of Interacting Partners?		Shelterin Complex Telomeric DNA Binding Nuclear Telomere Cap Complex Telomere Capping Regulation Of Telomere Maintenance Via Telomerase Telomere Assembly Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Telomere Maintenance Regulation Of Telomere Maintenance Negative Regulation Of Cellular Component Organization Cul5-RING Ubiquitin Ligase Complex Telomere Organization Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of DNA Metabolic Process Regulation Of Carbohydrate Catabolic Process Protein Modification Process Positive Regulation Of Telomere Maintenance Telomere Maintenance Via Telomerase Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cellular Component Organization Negative Regulation Of Chromosome Organization RNA-templated DNA Biosynthetic Process Chromosome, Telomeric Region Regulation Of Protein Localization Positive Regulation Of Organelle Organization Telomere Maintenance Via Telomere Lengthening Chromosome Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Chromosome Organization Protein K48-linked Ubiquitination Positive Regulation Of Metabolic Process Macromolecule Metabolic Process Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Chromosome Organization Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Regulation Of Cellular Component Organization Organelle Organization Intracellular Signal Transduction Protein Glycosylation Macromolecule Glycosylation Positive Regulation Of DNA Metabolic Process	Membrane Protein Binding Ascorbate Homeostasis Transmembrane Monodehydroascorbate Reductase Activity Endoplasmic Reticulum Membrane Endoplasmic Reticulum Glutamine Transport L-glutamine Transmembrane Transporter Activity
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