CKB and SERP2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CKB	SERP2
Gene Name		creatine kinase, brain	stress-associated endoplasmic reticulum protein family member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Vesicular Exosome	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding
	Biological Process	Creatine Metabolic Process Phosphorylation Substantia Nigra Development Cellular Chloride Ion Homeostasis Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process	Protein Transport
Pathways		Metabolism of amino acids and derivatives Creatine metabolism
Drugs		Creatine
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ACD ASB9 CKM ILK MLH1 POT1 PPP1CA SERP2 TAB1 TERF1 TINF2 TRIM63	3 interactors: CCDC155 CKB EWSR1
Entrez ID		1152	387923
HPRD ID		00423	16590
Ensembl ID		ENSG00000166165	ENSG00000151778
Uniprot IDs		P12277	Q8N6R1
PDB IDs		3B6R 3DRB 3DRE
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Negative Regulation Of DNA Metabolic Process Telomere Assembly Negative Regulation Of DNA Replication Telomere Maintenance Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Regulation Of DNA Replication Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Biosynthetic Process Regulation Of Chromosome Organization Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of DNA Metabolic Process Regulation Of Organelle Organization RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Chromosome Organization Protein Localization To Chromosome DNA Metabolic Process Positive Regulation Of Transferase Activity Cellular Component Assembly Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Transferase Activity Positive Regulation Of DNA Replication Negative Regulation Of Protein ADP-ribosylation Meiotic Metaphase I Plate Congression Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Meiotic Spindle Midzone Assembly Phosphocreatine Biosynthetic Process Cell Aging Cellular Metabolic Process Positive Regulation Of Organelle Organization Regulation Of Protein ADP-ribosylation Negative Regulation Of Mitotic Recombination Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomere Formation Via Telomerase Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Cellular Component Organization	Chromosome Localization To Nuclear Envelope Involved In Synapsis Cellular Chloride Ion Homeostasis Chloride Ion Homeostasis Creatine Metabolic Process
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