LINC00624 and G6PD

Number of citations of the paper that reports this interaction (PubMedID 36252997)
50

Data Source:
BioGRID (unspecified method)

		LINC00624	G6PD
Description		long intergenic non-protein coding RNA 624	glucose-6-phosphate dehydrogenase
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Membrane Centriolar Satellite Extracellular Exosome
	Molecular Function		Glucose-6-phosphate Dehydrogenase Activity Protein Binding D-glucose Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On CH-OH Group Of Donors Carbohydrate Binding Identical Protein Binding Protein Homodimerization Activity NADP Binding
	Biological Process		Glucose Metabolic Process Pentose-phosphate Shunt Lipid Metabolic Process Cholesterol Biosynthetic Process NADP+ Metabolic Process NADPH Regeneration Glutathione Metabolic Process Pentose-phosphate Shunt, Oxidative Branch Response To Iron(III) Ion Pentose Biosynthetic Process Substantia Nigra Development Response To Food Cellular Response To Oxidative Stress Erythrocyte Maturation Regulation Of Neuron Apoptotic Process Response To Ethanol Ribose Phosphate Biosynthetic Process Glucose 6-phosphate Metabolic Process Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			TP53 Regulates Metabolic Genes Pentose phosphate pathway NFE2L2 regulates pentose phosphate pathway genes
Drugs			Glycolic acid Nicotinamide adenine dinucleotide phosphate 16-Bromoepiandrosterone Artenimol
Diseases			Anemia due to disorders of glutathione metabolism, including: Glucose-6-phosphate dehydrogenase (G6PD) deficiency; Glutathione peroxidase (GPX) deficiency; Gamma-glutamylcysteine synthetase (GCLC) deficiency; Glutathione synthetase (GSS) deficiency Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS		Body mass index and systolic blood pressure (bivariate analysis) ( 33539483) End-stage kidney disease ( 31178898) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 31562340) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) Waist circumference adjusted for body mass index ( 28552196)	Bilirubin levels ( 19419973) Glycated hemoglobin levels ( 28898252 31213470 34059833) Hemoglobin levels ( 26366553) hemolysis of donated blood (oxidative) ( 34014839) Mean corpuscular hemoglobin ( 28453575) Mean corpuscular volume ( 28453575) Red blood cell count ( 28453575) Red blood cell traits ( 23446634 23696099) Red cell distribution width ( 28453575)
Interacting Genes		38 interacting genes: ACTA1 ACTC1 ADAR ALB CCT2 CCT4 CPNE3 DDX42 DDX5 EIF2AK2 FUBP3 G6PD H2BC18 HDAC6 HNRNPL HNRNPM HNRNPU HRNR ILF3 MCCC1 MCCC2 NONO PARP1 PTBP1 PTBP2 PTBP3 SERBP1 SFPQ SND1 SRRT STAU1 STAU2 TRIM28 TUBA1B TUBA1C UBAP2L YBX3 ZNF354C	5 interacting genes: CDC42 LINC00624 LINC01554 PAK4 SUMO4
Entrez ID		100289211	2539
HPRD ID			02377
Ensembl ID		ENSG00000278811	ENSG00000160211
Uniprot IDs			A0A384NL00 P11413
PDB IDs			1QKI 2BH9 2BHL 5UKW 6E07 6E08 6JYU 6VA0 6VA7 6VA8 6VA9 6VAQ 7SEH 7SEI 7SNF 7SNG 7SNH 7SNI 7TOE 7TOF 7UAG 7UAL 7UC2 7ZVD
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Localization Nucleic Acid Binding Double-stranded RNA Binding MRNA Processing MRNA Binding Negative Regulation Of Macromolecule Biosynthetic Process MRNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Viral Genome Replication Negative Regulation Of Metabolic Process Dendritic Transport Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression RNA Splicing Regulation Of Viral Life Cycle RNA Processing Cytoskeleton-dependent Intracellular Transport Alternative MRNA Splicing, Via Spliceosome Regulation Of Viral Process RNA Metabolic Process Cell Body Nucleus Axo-dendritic Transport Paraspeckles Regulation Of Macromolecule Biosynthetic Process Intracellular MRNA Localization Extracellular Exosome Regulation Of RNA Splicing Methylcrotonoyl-CoA Carboxylase Complex Methylcrotonoyl-CoA Carboxylase Activity Regulation Of Telomere Maintenance Via Telomere Lengthening Pre-mRNA Binding Cytoplasm Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Dendritic Transport Of Messenger Ribonucleoprotein Complex Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Response To Chemical Stress Negative Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Regulatory NcRNA-mediated Gene Silencing Transport Along Microtubule Binding Of Sperm To Zona Pellucida Mesenchyme Migration ScaRNA Localization To Cajal Body
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?