LSM14A and MYCBP2

Number of citations of the paper that reports this interaction (PubMedID 21653829)
54

Data Source:
BioGRID (two hybrid)

		LSM14A	MYCBP2
Description		LSM14A mRNA processing body assembly factor	MYC binding protein 2
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GO Annotations	Cellular Component	P-body Cytoplasm Spindle Cytosol Cytoskeleton Cytoplasmic Stress Granule Cytoplasmic Ribonucleoprotein Granule Mitotic Spindle Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Membrane Axon Cell Projection
	Molecular Function	Double-stranded DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Transferase Activity Small GTPase Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Translation Negative Regulation Of Translation P-body Assembly Stress Granule Assembly RIG-I Signaling Pathway Defense Response To Virus Positive Regulation Of Type I Interferon-mediated Signaling Pathway Mitotic Spindle Assembly	Axon Guidance Motor Neuron Axon Guidance Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Rhythmic Process Cell Morphogenesis Involved In Neuron Differentiation Neuromuscular Process Regulation Of Cytoskeleton Organization Axon Development Protein K48-linked Ubiquitination Regulation Of Axon Guidance
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062) Disease progression in age-related macular degeneration ( 29346644) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		4 interacting genes: CEBPA CSNK2A1 MYCBP2 OGT	50 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 BTG3 CALM1 CD81 CEBPA CFL1 CUEDC2 DHRS4L2 DSCR9 DYRK1A ERBB3 FHL3 FSCN1 HSP90AB1 HUNK IGFBP6 LCOR LDHB LSM14A MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 RSPH1 SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ
Entrez ID		26065	23077
HPRD ID		12697	10104
Ensembl ID		ENSG00000257103	ENSG00000005810
Uniprot IDs		Q8ND56	O75592
PDB IDs		6F9W	5O6C 6T7F
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Sin3-type Complex Rhythmic Process Regulation Of Proteolysis Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Circadian Regulation Of Gene Expression Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Chromatin DNA Binding Negative Regulation Of Protein Metabolic Process Protein Localization To Vacuole RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Translational Initiation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Circadian Rhythm Negative Regulation Of Proteolysis Response To Nutrient Response To Vitamin B2 C/EBP Complex Negative Regulation Of Macromolecule Metabolic Process Macroautophagy Regulation Of Synapse Assembly CHOP-C/EBP Complex Negative Regulation Of Metabolic Process Negative Regulation Of Translation Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Protein O-acetylglucosaminyltransferase Activity Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Carbohydrate Homeostasis Glucose Homeostasis Positive Regulation Of Protein Catabolic Process White Fat Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of Aggrephagy Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Post-translational Protein Modification	Cytoplasm Intracellular Signal Transduction
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