LSM14A

Description		LSM14A mRNA processing body assembly factor
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GO Annotations	Cellular Component	P-body Cytoplasm Spindle Cytosol Cytoskeleton Cytoplasmic Stress Granule Cytoplasmic Ribonucleoprotein Granule Mitotic Spindle Ribonucleoprotein Complex
	Molecular Function	Double-stranded DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of Translation Negative Regulation Of Translation P-body Assembly Stress Granule Assembly RIG-I Signaling Pathway Defense Response To Virus Positive Regulation Of Type I Interferon-mediated Signaling Pathway Mitotic Spindle Assembly
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062) Disease progression in age-related macular degeneration ( 29346644) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		4 interacting genes: CEBPA CSNK2A1 MYCBP2 OGT
Entrez ID		26065
HPRD ID		12697
Ensembl ID		ENSG00000257103
Uniprot IDs		Q8ND56
PDB IDs		6F9W
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Sin3-type Complex Rhythmic Process Regulation Of Proteolysis Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Circadian Regulation Of Gene Expression Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Chromatin DNA Binding Negative Regulation Of Protein Metabolic Process Protein Localization To Vacuole RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Translational Initiation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Circadian Rhythm Negative Regulation Of Proteolysis Response To Nutrient Response To Vitamin B2 C/EBP Complex Negative Regulation Of Macromolecule Metabolic Process Macroautophagy Regulation Of Synapse Assembly CHOP-C/EBP Complex Negative Regulation Of Metabolic Process Negative Regulation Of Translation Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Protein O-acetylglucosaminyltransferase Activity Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Carbohydrate Homeostasis Glucose Homeostasis Positive Regulation Of Protein Catabolic Process White Fat Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of Aggrephagy Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Post-translational Protein Modification
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