MPC2 and RHBDD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MPC2	RHBDD2
Description		mitochondrial pyruvate carrier 2	rhomboid domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Membrane Inner Mitochondrial Membrane Protein Complex	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Pyruvate Transmembrane Transporter Activity	Serine-type Endopeptidase Activity Signal Recognition Particle Binding Protein Binding
	Biological Process	Pyruvate Decarboxylation To Acetyl-CoA Pyruvate Import Into Mitochondria Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	Endoplasmic Reticulum Unfolded Protein Response ERAD Pathway
Pathways		Pyruvate metabolism
Drugs
Diseases
GWAS			Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		12 interacting genes: APOC1 CIDEB DIABLO MICOS10 NEAT1 RHBDD2 RPLP1 SNX1 SPG21 SYT16 TEX44 TIMM17B	60 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NEDD4 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SLC71A3P SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30 YAP1
Entrez ID		25874	57414
HPRD ID		08525	11492
Ensembl ID		ENSG00000143158	ENSG00000005486
Uniprot IDs		O95563	Q6NTF9
PDB IDs		8YW6 8YW8 8YW9 9KNW 9KNX 9KNY 9MNW 9MNX 9MNY 9MNZ 9MO0
Enriched GO Terms of Interacting Partners?		Very-low-density Lipoprotein Particle Assembly Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Regulation Of Triglyceride Metabolic Process Negative Regulation Of Phosphatidylcholine Catabolic Process	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Synaptic Transmission, Dopaminergic Mitochondrial Envelope Mitochondrion Organization Apoptotic Signaling Pathway Response To Amphetamine Dopamine Metabolic Process Response To Alkaloid Regulation Of Catecholamine Secretion Protein Binding Response To Amine Membrane Epithelial Cell Proliferation Mitochondrial Membrane Bcl-2 Family Protein Complex Intrinsic Apoptotic Signaling Pathway Mitochondrial Matrix Catecholamine Catabolic Process Catecholamine Metabolic Process Dopamine Catabolic Process Protein Localization To Mitochondrion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?