RHBDD2 and SDHD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHBDD2	SDHD
Description		rhomboid domain containing 2	succinate dehydrogenase complex subunit D
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Envelope Mitochondrial Inner Membrane Membrane Respiratory Chain Complex II (succinate Dehydrogenase)
	Molecular Function	Serine-type Endopeptidase Activity Signal Recognition Particle Binding Protein Binding	Protein Binding Succinate Dehydrogenase (quinone) Activity Electron Transfer Activity Heme Binding Metal Ion Binding Ubiquinone Binding
	Biological Process	Endoplasmic Reticulum Unfolded Protein Response ERAD Pathway	Tricarboxylic Acid Cycle Mitochondrial Electron Transport, Succinate To Ubiquinone Proton Motive Force-driven Mitochondrial ATP Synthesis Regulation Of Catecholamine Secretion Cellular Response To Hypoxia
Pathways			Respiratory electron transport Citric acid cycle (TCA cycle) Maturation of TCA enzymes and regulation of TCA cycle
Drugs			Hexachlorophene 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases			Carcinoid
GWAS		Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)	Brain morphology (MOSTest) ( 32665545) General risk tolerance (MTAG) ( 30643258) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		60 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NEDD4 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SLC71A3P SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30 YAP1	5 interacting genes: F2RL1 GPR35 MTNR1B RHBDD2 SLC13A1
Entrez ID		57414	6392
HPRD ID		11492	04069
Ensembl ID		ENSG00000005486	ENSG00000204370
Uniprot IDs		Q6NTF9	A0A0S2Z4H7 A0A0S2Z4J3 O14521
PDB IDs			8GS8
Enriched GO Terms of Interacting Partners?		Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Synaptic Transmission, Dopaminergic Mitochondrial Envelope Mitochondrion Organization Apoptotic Signaling Pathway Response To Amphetamine Dopamine Metabolic Process Response To Alkaloid Regulation Of Catecholamine Secretion Protein Binding Response To Amine Membrane Epithelial Cell Proliferation Mitochondrial Membrane Bcl-2 Family Protein Complex Intrinsic Apoptotic Signaling Pathway Mitochondrial Matrix Catecholamine Catabolic Process Catecholamine Metabolic Process Dopamine Catabolic Process Protein Localization To Mitochondrion	Negative Regulation Of Insulin Secretion Negative Regulation Of Peptide Secretion G Protein-coupled Receptor Activity Negative Regulation Of Protein Secretion Negative Regulation Of Hormone Secretion Negative Regulation Of Transport Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Proteinase-activated Receptor Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Vessel Diameter Maintenance Negative Regulation Of Secretion By Cell Positive Regulation Of Glomerular Filtration G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Protein Transport Regulation Of Renin Secretion Into Blood Stream Regulation Of Tube Size Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Establishment Of Protein Localization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Sodium:sulfate Symporter Activity Monoatomic Anion:sodium Symporter Activity Regulation Of Insulin Secretion Negative Regulation Of Secretion Positive Regulation Of Killing Of Cells Of Another Organism Melatonin Receptor Activity Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Peptide Hormone Secretion Mature Conventional Dendritic Cell Differentiation Thrombin-activated Receptor Activity Regulation Of Neuronal Action Potential Negative Regulation Of Protein Localization Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Positive Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Hormone Secretion Regulation Of Protein Secretion Vascular Process In Circulatory System C-X-C Chemokine Receptor Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Secondary Active Sulfate Transmembrane Transporter Activity Signal Recognition Particle Binding Regulation Of Glomerular Filtration Thrombin-activated Receptor Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?