RHBDD2 and TSR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHBDD2	TSR1
Description		rhomboid domain containing 2	TSR1 ribosome maturation factor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Serine-type Endopeptidase Activity Signal Recognition Particle Binding Protein Binding	RNA Binding GTPase Activity Protein Binding GTP Binding U3 SnoRNA Binding
	Biological Process	Endoplasmic Reticulum Unfolded Protein Response ERAD Pathway	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Ribosome Biogenesis
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)	Aortic root size ( 19584346) Appendicular lean mass ( 33097823) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 25056061 29483656)
Interacting Genes		60 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NEDD4 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SLC71A3P SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30 YAP1	4 interacting genes: BMPR2 CIDEB RHBDD2 SUMO2
Entrez ID		57414	55720
HPRD ID		11492	07681
Ensembl ID		ENSG00000005486	ENSG00000167721
Uniprot IDs		Q6NTF9	Q2NL82
PDB IDs			6G18 6G4S 6G4W 6G51 6G53 6ZMT 6ZN5 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 8ZDC 8ZDD
Enriched GO Terms of Interacting Partners?		Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Synaptic Transmission, Dopaminergic Mitochondrial Envelope Mitochondrion Organization Apoptotic Signaling Pathway Response To Amphetamine Dopamine Metabolic Process Response To Alkaloid Regulation Of Catecholamine Secretion Protein Binding Response To Amine Membrane Epithelial Cell Proliferation Mitochondrial Membrane Bcl-2 Family Protein Complex Intrinsic Apoptotic Signaling Pathway Mitochondrial Matrix Catecholamine Catabolic Process Catecholamine Metabolic Process Dopamine Catabolic Process Protein Localization To Mitochondrion	Positive Regulation Of Axon Extension Involved In Axon Guidance Negative Regulation Of Chondrocyte Proliferation Regulation Of Lung Blood Pressure Aortic Valve Development Lymphatic Endothelial Cell Differentiation BMP Receptor Activity Pulmonary Valve Development Tricuspid Valve Morphogenesis Venous Blood Vessel Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Activin Receptor Activity, Type II Endochondral Bone Morphogenesis Transforming Growth Factor Beta Receptor Activity Semi-lunar Valve Development Mitral Valve Morphogenesis Lipid Droplet Fusion Signal Recognition Particle Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Regulation Of Axon Extension Involved In Axon Guidance Maternal Placenta Development Lung Vasculature Development Lymphangiogenesis Negative Regulation Of Vasoconstriction Cellular Response To Stress Endocardial Cushion Development Pharyngeal Arch Artery Morphogenesis Retina Vasculature Development In Camera-type Eye Endothelial Cell Apoptotic Process Atrial Septum Morphogenesis Protein Tag Activity COPI-coated Vesicle COPII Vesicle Coat Lipid Transfer Activity Very-low-density Lipoprotein Particle Assembly Regulation Of Cell Proliferation Involved In Heart Morphogenesis COPII-coated Vesicle Cargo Loading Atrioventricular Valve Morphogenesis Response To Nutrient Levels SUMO Transferase Activity BMP Binding Heart Valve Development Chondrocyte Development Negative Regulation Of Systemic Arterial Blood Pressure Execution Phase Of Apoptosis Phosphatidic Acid Binding Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Ubiquitin-like Protein Ligase Binding Outflow Tract Septum Morphogenesis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?