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MPC2

Description mitochondrial pyruvate carrier 2
Image
GO Annotations Cellular Component
  • Nucleus
  • Mitochondrion
  • Mitochondrial Inner Membrane
  • Membrane
  • Inner Mitochondrial Membrane Protein Complex
Molecular Function
  • Protein Binding
  • Identical Protein Binding
  • Pyruvate Transmembrane Transporter Activity
Biological Process
  • Pyruvate Decarboxylation To Acetyl-CoA
  • Pyruvate Import Into Mitochondria
  • Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways
  • Pyruvate metabolism
Drugs
Diseases
GWAS
Interacting Genes 12 interacting genes: APOC1 CIDEB DIABLO MICOS10 NEAT1 RHBDD2 RPLP1 SNX1 SPG21 SYT16 TEX44 TIMM17B
Entrez ID 25874
HPRD ID 08525
Ensembl ID ENSG00000143158
Uniprot IDs O95563
PDB IDs 8YW6 8YW8 8YW9 9KNW 9KNX 9KNY 9MNW 9MNX 9MNY 9MNZ 9MO0
Enriched GO Terms of Interacting Partners?
  • Very-low-density Lipoprotein Particle Assembly
  • Protein-lipid Complex Assembly
  • Plasma Lipoprotein Particle Assembly
  • Regulation Of Triglyceride Metabolic Process
  • Negative Regulation Of Phosphatidylcholine Catabolic Process
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